Results 281 to 290 of about 604,484 (380)
High-throughput biomedical relation extraction for semi-structured web articles empowered by large language models. [PDF]
Zhou S, Yu S.
europepmc +1 more source
A Multi‐Stimuli‐Responsive Pd2L4 Metallacage for Amino Acid Sensing
A multi‐stimuli‐responsive metallacage was constructed via a bottom‐up design strategy, and its stimuli‐responsive behaviors were investigated in response to basic/acidic reagents, naphthalene disulfonate, and thiol‐containing amino acids, accompanied by remarkable structural transformations and fluorescence variations.
Dongpu Wu +7 more
wiley +1 more source
A structural machine learning approach for rapid prediction of thermodynamically destabilizing tyrosine phosphorylations. [PDF]
Woodard J +8 more
europepmc +1 more source
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone +13 more
wiley +1 more source
A meta-learning framework to mitigate negative transfer in transfer learning applicable to drug design. [PDF]
Mera A, Vogt M, Bajorath J.
europepmc +1 more source
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio +12 more
wiley +1 more source
Cellular phospho-signaling map of the enigmatic serine/threonine kinase MAST2. [PDF]
Fathima I +7 more
europepmc +1 more source

