Results 281 to 290 of about 521,154 (335)

Entwicklung von chemischen Initiatoren der Dimerisierung von HaloTag und SNAP‐Tag zur Untersuchung von Signaltransduktion induziert durch Rezeptor‐Oligomerisierung

open access: yesAngewandte Chemie, EarlyView.
Die Kontrolle von Protein‐Interaktionen ist entscheidend für das Verständnis von Signaltransduktionsprozessen. Antikörperbasierte Methoden stoßen dabei an ihre Grenzen, doch chemische Dimerisierungsinduktoren (CIDs), die HaloTags und SNAP‐Tags nutzen, ermöglichen eine präzise Steuerung.
Michael Trumpp   +8 more
wiley   +1 more source

Novel kinase-activating genetic events in non-small cell lung carcinomas. [PDF]

open access: yesExplor Target Antitumor Ther
Preobrazhenskaya EV   +9 more
europepmc   +1 more source

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

open access: yesAngewandte Chemie International Edition, EarlyView.
Controlling protein interactions is key to studying signaling. Antibody methods have limits, but chemical inducers of dimerization (CIDs) using HaloTags and SNAP‐Tags offer precise control. We present CIDs to covalently link heteromers with varied linkers and a FRET‐based sensor.
Michael Trumpp   +8 more
wiley   +1 more source

An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis. [PDF]

open access: yesCell Genom
Zhang Y   +12 more
europepmc   +1 more source

Green and Sustainable Production of Edible Pullulan/Whey Nanofibers Loaded With Black Cumin (Nigella sativa) Waste Extract

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT In this study, the electrospinning method was used to create green synthesis sustainable pullulan and whey protein nanofibers loaded with black cumin waste extract. FE‐SEM imaging, FTIR, XRD, DSC, total phenolic content determination, total antioxidant activity determination, and antibacterial activity assessment were used to characterize the ...
Özlem Zambak, Sami Gökhan Özkal
wiley   +1 more source

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