Results 281 to 290 of about 611,533 (383)

Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease. [PDF]

Alzheimers Dement
Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu AT, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH.   +17 more
europepmc   +1 more source

Simultaneous Visualization of Distinct Posttranslational Modification States of β‐Catenin Using Genetic Code Expansion and Click Chemistry

ChemBioChem, EarlyView.
A method to visualize, within the same cell, three distinct posttranslational forms of β‐catenin: wild‐type, phosphomimetic (T41E), and synthetic T41C‐GlcNAc, using genetic code expansion and fluorescence microscopy is developed. This strategy reveals how modifications at T41 alter β‐catenin localization and stability. A novel strategy based on genetic
Christer Abou Anny, Sébastien Nouaille, Isabelle Huvent, Corentin Spriet, Céline Schulz, Fabrice Bray, Régis Fauré, Tony Lefebvre, Christophe Biot   +8 more
wiley   +1 more source

Serum Metabolomics Reveals Potential Differences in Gut Microbiota-Associated Metabolites in Twins Discordant for Type 1 Diabetes. [PDF]

Diabetes
Flammer ER, Christopher MW, Powers ER, Broncucia H, Steck AK, Gitelman SE, Garrett TJ, Ismail HM.   +7 more
europepmc   +1 more source

The Effects of Analogues of Threonine and of Isoleucine on the Properties of Threonine Deaminase

Cold Spring Harbor Symposia on Quantitative Biology, 1963
M. Freundlich, H. E. Umbarger
openaire   +1 more source

A Stable Bioisostere of Ester‐Linked Ubiquitin Chains Enables Decoding of Protein Interactors

ChemBioChem, EarlyView.
An ester‐to‐amide analog of an ester‐linked ubiquitin dimer is chemically synthesized through a convergent approach involving the sequential chemoselective ligation of three peptide fragments generated through Fmoc‐based solid‐phase peptide synthesis. The hydrolysis‐resistant ubiquitin dimer served as a chemical probe in the identification of potential
Yoshinori Taguchi, Takuya Tomita, Takuma Nishizawa, Dai Nakamura, Showmitra Saha, Takanori Oyoshi, Kohei Sato, Nobuyuki Mase, Yasushi Saeki, Tetsuo Narumi   +9 more
wiley   +1 more source

Identification of Amino Acids That Regulate Angiogenesis and Alter Pathogenesis of a Mouse Model of Choroidal Neovascularization. [PDF]

Nutrients
Li C, Wu J, Zhao Y, Zhu J, Zhu X, Chen Y, Wu J.   +6 more
europepmc   +1 more source

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos, Shirley De Lima Sampaio, Helen E. Hayes, Gary J. Duncan, Donna Henderson, Nicholas J. Vaughan, Wendy R. Russell, Madalina Neacsu   +7 more
wiley   +1 more source

Multi-Omics Analysis Reveals the Regulation of Amino Acid Biosynthesis in <i>Cyclocarya paliurus</i> Leaves Under Salt Stress. [PDF]

Int J Mol Sci
Zhang L, Hong K, Zhang Z, Shang X, Fang S.   +4 more
europepmc   +1 more source

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

Nature, 2013
D. H. Ebert, Harrison W. Gabel, Nathaniel D. Robinson, Nathaniel R Kastan, Linda S. Hu, Sonia Cohen, Adrija Navarro, Matthew J. Lyst, R. Ekiert, A. Bird, M. Greenberg   +10 more
semanticscholar   +1 more source

Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid

ChemistryEurope, EarlyView.
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai, Youhi Hwang, Hiroki Umeda, Taka Sawazaki, Ikumi Tomizawa, Maiko Ono, Makoto Higuchi, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Harunobu Mitsunuma, Motomu Kanai   +11 more
wiley   +1 more source