Results 291 to 300 of about 604,484 (380)

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

open access: yesNature, 2013
D. H. Ebert   +10 more
semanticscholar   +1 more source

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen   +10 more
wiley   +1 more source

Protein chemical synthesis by serine and threonine ligation

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Yinfeng Zhang   +4 more
semanticscholar   +1 more source

Comparison of the effects of metformin, citral, Cymbopogon citratus extract and silver nanoparticles of Cymbopogon citratus extract on oxidative stress indices and Nrf2 levels in experimental type 2 diabetes in rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The experimental type 2 diabetes model in rats induced by streptozotocin and nicotinamide showed that silver nanoparticles synthesized from lemongrass extract modulate blood glucose, water and food intake, and enhance antioxidant enzyme synthesis and weight gains.
Milad Faraji   +6 more
wiley   +1 more source

Biocatalytic synthesis of β-hydroxy tryptophan regioisomers.

open access: yesOrg Biomol Chem
Bruffy SK   +3 more
europepmc   +1 more source

Assessing the therapeutic potential of Tirzepatide in modulating inflammatory responses and mitigating acute pancreatitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Tirzepatide: A peptide‐based GLP‐1/GIP receptor agonist, tested on L‐Arginine‐induced pancreatitis. Lipase/Amylase Levels: Initially elevated due to inflammation but normalized with Tirzepatide. Inflammatory Response: Reduction in pro‐inflammatory cytokines (IL‐6) and enhancement of anti‐inflammatory cytokines (IL‐4, IL‐10).
Razan Alawaji   +9 more
wiley   +1 more source

Phosphorylation as a candidate regulatory mechanism for effector recruitment to tankyrase. [PDF]

open access: yesR Soc Open Sci
Broadway BJ   +5 more
europepmc   +1 more source

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