Results 291 to 300 of about 514,103 (332)

A missense mutation in the γD crystallin gene (CRYGD) associated with autosomal dominant coral-like cataract linked to chromosome 2q [PDF]

, 2004
Andley, Usha P, Mackay, Donna S, Shiels, Alan   +2 more
core   +1 more source

KnowVolution Of An Efficient Polyamidase Through Molecular Dynamics Simulations Of Incrementally Docked Oligomeric Substrates

ChemSusChem, Accepted Article.
Management of synthetic polymer waste is one of the most pressing challenges for society today. Enzymatic recycling of polycondensates like polyamides (PA), however, remains limited due to a lack of efficient polyamidases. This study reports the directed evolution of the polyamidase NylCp2‐TS. Key positions involved in enzyme‐substrate interactions and
Hendrik Puetz, Alexander-Maurice Illig, Mariia Vorobii, Christoph Janknecht, Francisca Contreras, Fabian Flemig, Ulrich Schwaneberg   +6 more
wiley   +1 more source

Functional kinome profiling reveals brain protein kinase signaling pathways and gene networks altered by acute voluntary exercise in rats. [PDF]

PLoS One
Lee CM, Nguyen J, Pope B, Imami AS, Ryan VWG, Sahay S, Mathis V, Pulvender P, Eby HM, Arvay T, Alganem K, Wegman-Points L, McCullunsmith R, Yuan LL.   +13 more
europepmc   +1 more source

β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

Developmental Dynamics, EarlyView.
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters, Lucas J. Guttieres, Mayline Goëb, Stanley J. Marjenberg, Mark Q. Martindale, Athula H. Wikramanayake   +5 more
wiley   +1 more source

PhosF3C: a feature fusion architecture with fine-tuned protein language model and conformer for prediction of general phosphorylation site. [PDF]

Brief Bioinform
Liu Y, Wang X, Zhong H, Zhai J, Gong X, Lu T.   +5 more
europepmc   +1 more source

The link of FOXO1 and FOXO4 transcription factors to development of the lens

Developmental Dynamics, EarlyView.
Abstract Background The FOXOs regulate the transcription of many genes, including ones directly linked to pathways required for lens development. However, this transcription factor family has rarely been studied in the context of development, including the development of the lens.
Rifah N. Gheyas, Ruby C. Williams, Kelly A. Ryan, A. Sue Menko   +3 more
wiley   +1 more source

The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of <i>Trypanosoma cruzi</i>. [PDF]

mSphere
Alencar MB, Girard RMBM, Crispim M, Baptista CG, Biran M, Bringaud F, Silber AM.   +6 more
europepmc   +1 more source

Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma

Eye &ENT Research, EarlyView.
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen, Zhe Zhang, Xueting Yang, Chao Li   +3 more
wiley   +1 more source

GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner. [PDF]

Commun Biol
Löbbert A, Lorz N, Matthees ESF, Rößler P, Hoffmann C, Gossert AD.   +5 more
europepmc   +1 more source

Prkci promotes colorectal cancer metastasis by phosphorylating and stabilizing Tgfbr1 to activate TGF-β signaling. [PDF]

Cell Commun Signal
Li P, Liu G, Zhang W, Li T.
europepmc   +1 more source