Results 61 to 70 of about 3,394,738 (297)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Evidence accumulator or decision threshold - which cortical mechanism are we observing?

open access: yesFrontiers in Psychology, 2012
Most psychological models of perceptual decision making are of the accumulation-to-threshold variety. The neural basis of accumulation in parietal and prefrontal cortex is therefore a topic of great interest in neuroscience.
Patrick eSimen
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epidemiology of Malaria Cases, Sunyani Municipality, Ghana, 2020

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Malaria is endemic in Ghana, accounting for about 40% of all Outpatient Department (OPD) diagnoses. Data on malaria is routinely collected as part of the IDSR monthly reporting forms. Sunyani municipality recorded 56,540 malaria cases in
Abdul Gafaru Mohammed   +6 more
doaj   +1 more source

The Witch(ES) of Aiaia: Gender, Immortality and the Chronotope in Madeline Miller’s Circe

open access: yesGender Studies, 2019
This article explores Madeline Miller’s Circe from the perspective of Bakhtin’s concept of the chronotope, the inseparability of space and time in fiction.
Macmillan Catherine
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Private Rented Sectors in the North and South of Ireland: A Case Study in Convergence Analysis

open access: yesJournal of Economic Development, Environment and People, 2015
The theme of this paper centres on the convergence and divergence of housing policy between two regimes inhabiting the same geographical space on the island of Ireland, as reflected in the development of the private rented sector (PRS) in both ...
Aideen Hayden   +3 more
doaj  

ENHANCING NETWORK PERFORMANCE WITH IMPROVED RANDOM EARLY DETECTION

open access: yesTạp chí Khoa học
Congestion has become an important issue affecting the performance of network systems. Active Queue Management (AQM) algorithms are crucial in ensuring network stability.
Vu Van Dien
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Threshold Phenomena

open access: yesRevista Filosófica de Coimbra
“Threshold Phenomena: Jacques Derrida and the Question of Hospitality” considers Jacques Derrida’s thinking of hospitality in light of his recently published two-year seminar from the mid-1990s on the topic.
Michael Naas
doaj   +1 more source

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