HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Expression of Concern: Economic policy uncertainty and stock market in G7 Countries: A panel threshold effect perspective. [PDF]
PLoS OnePLOS One Editors.
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Spatial spillover and threshold effect of green development efficiency on urban human settlement resilience in Yangtze River Delta urban agglomeration. [PDF]
PLoS One, 2023 Wang Z, Xu X, Zhang J.
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Threshold effect of visceral adiposity index on suicidal ideation: a mediation analysis through fasting blood glucose. [PDF]
Front PsychiatryZhang L, Zhang W, Hang L.
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Economic Growth and Extreme Poverty in Sub-Saharan African Countries: Non-Linearity and Governance Threshold Effect. [PDF]
J Knowl Econ, 2023 Saidi Y, Labidi MA, Ochi A.
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
The threshold effect of a body shape index on phenotypic age acceleration in U.S. adults: Insights from NHANES 1999 to 2010. [PDF]
Medicine (Baltimore)Li YJ, Li YJ.
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Research on the Heterogeneity Threshold Effect of Foreign Direct Investment and Corporate Social Responsibility on Haze Pollution. [PDF]
Int J Environ Res Public Health, 2023 Wang Z, Ma Y, Wang S, Wang Y.
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