Results 71 to 80 of about 11,447,501 (301)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Threshold Effect and Financial Intermediation in Economic Development [PDF]

This paper analyzes the theoretical finance-growth nexus. Using the Neoclassical growth framework, we raise a new issue where our finance-growth nexus has multiple stationary states with threshold effect.
Augier, Laurent, Soedarmono, Wahyoe
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Effect of Myopia on Contrast Thresholds

Investigative Opthalmology & Visual Science, 2007
To examine the relationship between the degree of myopia and foveally measured contrast thresholds.Monocular thresholds for positive and negative contrast were obtained from 60 myopes (-1.0 to -8.0 D) and 20 emmetropes of similar age. The contrast thresholds were measured at different background luminance levels, photopic and mesopic, by using a visual
openaire   +2 more sources

Threshold signatures from VOLE

, 2023
reservedThe focus of this thesis is on threshold digital signatures and in particular on Schnorr signatures (1991). Following the expiration of its patent in 2008, Schnorr signature has gained significance in the realm of digital signatures due to its ...
MARCHIORO, ALESSANDRO
core  

The Impact of Digital Economy Development on Regional Income Gaps: A Perspective on Multidimensional Inequality Decomposition and Threshold Effects

Mathematics
This paper investigates the impact of digital economy development on regional income gaps within provinces in China, focusing on the underlying mechanisms and multidimensional threshold effects.
Jing Ruan, Lu Zou, Ruiqi Liu, Hongyun Pan   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Land Resource Allocation and Green Economic Development: Threshold Effect on Local Government Functional Performance in China

Land
Given the increasing scarcity of natural resources and the global imperative for sustainable development, the relationship between land resource allocation and green economic efficiency remains crucial but underexplored.
Yuyuan Wen, Fangfang Li, Zhiqing Wang
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effect of oxide interface roughness on the threshold voltage fluctuations in decanano MOSFETs with ultrathin gate oxides [PDF]

, 2000
In this paper we use the density gradient (DG) simulation approach to study, in 3D, the effect of local oxide thickness fluctuations on the threshold voltage of decanano MOSFETs on a statistical scale.
Kalna, K., Asenov, A., A. Asenov, S. Kaya   +3 more
core   +1 more source