Results 81 to 90 of about 1,407,158 (281)

Distributed classifier based on genetically engineered bacterial cell cultures

open access: yes, 2014
We describe a conceptual design of a distributed classifier formed by a population of genetically engineered microbial cells. The central idea is to create a complex classifier from a population of weak or simple classifiers.
Didovyk, Andriy   +5 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Modeling an Electrically Driven Graphene-Nanoribbon Laser for Optical Interconnects

open access: yes, 2013
Graphene has two very important optical properties of population inversion of electrons, and broadband optical gain. As a result, graphene has potential for use in lasers and amplifiers.
Shan, Guangcun, Shek, Chan-Hung
core   +1 more source

Higher-Order Threshold Implementation of the AES S-Box [PDF]

open access: yes, 2016
H2020 644052 ...
De Cnudde, Thomas   +4 more
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Threshold Implementations with Non-uniform Inputs

open access: yes
sponsorship: We thank Tim Beyne for the interesting discussions. This work was supported by CyberSecurity Research Flanders with reference number VR20192203. (CyberSecurity Research Flanders|VR20192203)
Dhooghe, Siemen, Ovchinnikov, Artemii
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Implementing Parallel Counters with Four-Valued Threshold Logic

open access: yesIEEE Transactions on Computers, 1979
Parallel counters are multiple-input circuits that count the number of their inputs that are in a given state. They are useful in implementing parallel multipliers, digital summers, digital correlators, and in other digital signal processing capacities. In this paper, the implementation of parallel counters with four-valued threshold logic is described
Current, K. Wayne, Mow, Douglas A.
openaire   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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