Results 41 to 50 of about 963,040 (323)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

COMPARISON OF RUSSIAN AND FOREIGN HYGIENIC PARAMETERS OF MEDICINES PERMISSIBLE EXPOSURE LIMIT

Разработка и регистрация лекарственных средств, 2019
Hygienic standardization of harmful substances in the air of the working area, aimed at maintaining the health of workers is an essential attribute of any chemical production, including pharmaceutical producing.
S. S. Rozhkov, A. V. Smirnov
doaj  

Identifying Thresholds for Similarity-Based Class Cohesion (SCC) Metrics

JITeCS (Journal of Information Technology and Computer Science), 2017
. The object-oriented design (OOD) concept can be used to implement a quality measurement program is based on the possibility of inter-relationship between attributes and methods in the class diagram and interaction between objects on a communication ...
Fajar Pradana, Bayu Priyambadha, Denny Sagita Rusdianto   +2 more
doaj   +1 more source

Exact Coupling Threshold for Structural Transition in Interconnected Networks [PDF]

, 2014
Interconnected networks are mathematical representation of systems where two or more simple networks are coupled to each other. Depending on the coupling weight between the two components, the interconnected network can function in two regimes: one where the two networks are structurally distinguishable, and one where they are not.
arxiv   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Potato, a Goldmine, Now a Biological Time Bomb: A Case Study of Uptake of Heavy Metals by Tubers of Potato in Jos-Nigeria

Journal of Applied Sciences and Environmental Management, 2023
The uptake and accumulation of heavy metals by plant roots occurs through an inter-related network of physiological and molecular mechanisms, including the binding of metals to extracellular exudates and cell wall components.
E. Oiganji, K. B. Emmanuel, M. L. Anisa, A. Ahmed   +3 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Threshold value of three dimensional bootstrap percolation [PDF]

, 2002
The following article deals with the critical value p_c of the three-dimensional bootstrap percolation. We will check the behavior of p_c for different lengths of the lattice and additionally we will scale p_c in the limit of an infinite lattice.
arxiv   +1 more source