Results 51 to 60 of about 407,044 (304)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Simulation of Pollutant Gas Dispersion on Case Study of Lontar 3 Coal Fired Power Plant in Addition into 1 x 660 MW Capacity in Kemiri, Tangerang District, Banten Province

Indonesian Journal of Chemistry, 2014
Air quality simulation has been performed for additional capacity of Banten 1 x 600 MW Coal Fired Power Plant toward air quality degradation in its surrounding environment.
Eko Sugiharto, Taufik Abdillah Natsir, Abdul Rozaq   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Effects of formaldehyde on the frog's mucociliary epithelium as a surrogate to evaluate air pollution effects on the respiratory epithelium

Brazilian Journal of Medical and Biological Research, 2001
The increasing use of alcohol as an alternative fuel to gasoline or diesel can increase emission of formaldehyde, an organic gas that is irritant to the mucous membranes.
C. Fló-Neyret, G. Lorenzi-Filho, M. Macchione, M.L.B. Garcia, P.H.N. Saldiva   +4 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Blood Lead Levels in Workers at Kooshk Lead and Zinc Mine

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2008
Introduction: The extensive use of Lead has led to health problems including CNS, anemia and other occupational poisoning among workers. To determine the blood lead levels in relation to demographic factors, this study was carried out.
AM Hakimian, MH Ehrampoush, A Barkhordari, MR Aminipour   +3 more
doaj  

Study on strength limit neighborhood range of gas-bearing coal rock under different loading conditions

Meitan kexue jishu
The occurrence mechanism of coal and gas outburst disasters is still unclear. According to the rheological hypothesis, gas-bearing coal and rock may enter the “strength limit neighborhood” under long-term load, and it is more likely to be destroyed by ...
Bo WANG, Shiji MA, Zhiyin TIAN, Yongzheng REN, Jun WANG, Wanpeng HUANG, Ling WANG   +6 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Formaldehyde Exposure and Irritative Effects on Medical Examiners, Pathologic Anatomy Post-Graduate Students and Technicians [PDF]

Iranian Journal of Public Health, 2010
Background: Exposure to formaldehyde (FA) causes irritative effects and induces nasopharyngeal cancer; the Interna­tional Agency for Research on Cancer (IARC, Lyon) classified FA as carcinogenic to humans, Group 1. Many studies have been published so far
L Vimercati, A Carrus, T Martino, I Galise, V Minunni, F Caputo, A Dell'Erba, G Assennato   +7 more
doaj   +1 more source

METHODOLOGY OF COST-UTILITY ANALYSIS IN PHARMACOECONOMICSTUDIES

Фармакоэкономика, 2015
pharmacoeconomic cost-utility analysis – CUA is at third place by popularity (10% of studies) among studies of pharmacoeconomic analysis. Main stages of these trials are as follows: cost analysis, utility analysis and results assessment.
R. I. Yagudina, I. V. Sorokovikov
doaj