Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
State estimator and convolutional neural networks-based fault localization approach for modern grids. [PDF]
Sci RepBhutto JA +7 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Eliminating single points of trust: a hybrid quantum and post-quantum blockchain with distributed key generation. [PDF]
Sci RepGoh KW +5 more
europepmc +1 more source
A Threshold Based Handover Triggering Scheme in Heterogeneous Wireless Networks
, 2014 Liming Chen +3 more
openalex +2 more sources
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Towards Heart Rate Estimation in Complex Multi-Target Scenarios: A High-Precision FMCW Radar Scheme Integrating HDBS and VLW. [PDF]
Sensors (Basel)Dong X +5 more
europepmc +1 more source
Soft thresholding schemes for multiple signal classification algorithm
, 2020 Sebastián Acuña +4 more
openalex +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Robust overlapping covert communication against partialband interference via chaotic multi-tone spread spectrum. [PDF]
Sci RepGuo S, Liu D, Fu Y.
europepmc +1 more source