Results 81 to 90 of about 1,268,925 (240)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Threshold Equalization for On-Line Signature Verification [PDF]

In on-line signature verification, complexity of signature shape can influence the value of the optimal threshold for individual signatures. Writer-dependent threshold selection has been proposed but it requires forgery data.
Nakanishi, Isao, 26716, 40032023, 80243377, 26715, 2512, ナカニシ, イサオ, Sakamoto, Hiroyuki, 100000543, 100000466, 4631, 415, 70263481, Fukui, Yutaka, Ito, Yoshio   +14 more
core   +1 more source

Dynamic Committee-based Hybrid Consensus Protocol for the DAG Blockchain

工程科学与技术
ObjectiveTo address the challenges of low throughput, high confirmation latency, and insufficient security in existing DAG-based blockchain systems, a Dynamic Committee-based Hybrid Consensus Protocol (DCHCP) for DAG blockchains is proposed.MethodsFirst,
ZHANG Xuewang, ZHANG Fengyi, XIE Haofei
doaj  

Provable Secure ID-based Proactive Threshold Signature in the Standard Model

工程科学与技术, 2010
:At present, the security of the identity based proactive threshold signature schemes was almost proved in the random oracle model, and the threshold values of these schemes were almost changeless.
Sun Hua, Zhou Fang, Yao xuanxia, Deng Zhongjun   +3 more
doaj  

90-gene signature assay for tissue origin diagnosis of brain metastases

Journal of Translational Medicine, 2019
Background Brain metastases (BM) are the most common intracranial tumors. 2–14% of BM patients present with unknown primary site despite intensive evaluations.
Yulong Zheng, Yongfeng Ding, Qifeng Wang, Yifeng Sun, Xiaodong Teng, Qiqi Gao, Weixiang Zhong, Xiaofeng Lou, Cheng Xiao, Chengshu Chen, Qinghua Xu, Nong Xu   +11 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Dual-proxy key-based threshold signature scheme for ship ad-hoc network

Tongxin xuebao, 2018
In order to solve the problem of message authentication under the conditions of the ship ad-hoc network (SANET),a signature scheme that does not depend on trusted certificate authorities and tamper-proof devices (TPD) was proposed by using the threshold ...
Ming XU, Xuru LI, Chaobin LIU, Yao MA
doaj   +2 more sources