Results 181 to 190 of about 1,445,591 (343)

The Threshold of Science [PDF]

, 1892

openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Elevating image segmentation with multilevel two-dimensional quantum representation. [PDF]

PLoS One
Bahaddad AA, Abdel-Khalek S, Alkhalaf S, AbdelSalam HM, Ishak AB, Aripov M.   +5 more
europepmc   +1 more source

Relations among Intensity, Time, and Temporary Threshold Shift [PDF]

, 1958
W. Dixon Ward, Aram Glorig, Diane L. Sklar   +2 more
openalex   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

GPR Feature Enhancement of Asphalt Pavement Hidden Defects Using Computational-Efficient Image Processing Techniques. [PDF]

Materials (Basel)
Xie S, Chen J, Cai M, Cheng Z, Wang S, Zhang Y.   +5 more
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Automated Cervical Nuclei Segmentation in Pap Smear Images Using Enhanced Morphological Thresholding Techniques. [PDF]

Diagnostics (Basel)
Mustafa WA, Khiruddin K, Saidi SA, Jamaludin KR, Hakimi H, Jamlos MA.   +5 more
europepmc   +1 more source

Diabetes Mellitus with an Unusually Low Renal Threshold for Sugar [PDF]

, 1936
W. W. Payne
openalex   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source