Results 61 to 70 of about 274,981 (298)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A novel thresholding based algorithm for detection of vertical root fracture in nonendodontically treated premolar teeth

open access: yesJournal of Medical Signals and Sensors, 2016
In this paper, an efficient algorithm is proposed for detection of vertical root fractures (VRFs) in periapical (PA), and cone-beam computed tomography (CBCT) radiographs of nonendodontically treated premolar teeth.
Masume Johari   +4 more
doaj  

An Embedded Application for Degraded Text Recognition

open access: yesEURASIP Journal on Advances in Signal Processing, 2005
This paper describes a mobile device which tries to give the blind or visually impaired access to text information. Three key technologies are required for this system: text detection, optical character recognition, and speech synthesis. Blind users and
Thillou Céline   +2 more
doaj   +1 more source

Prolonged SARS-CoV-2 infection following rituximab treatment: clinical course and response to therapeutic interventions correlated with quantitative viral cultures and cycle threshold values [PDF]

open access: gold, 2022
Christina S. Thornton   +12 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

An Overview of Segmentation Algorithms for the Analysis of Anomalies on Medical Images

open access: yesJournal of Intelligent Systems, 2018
Human disease identification from the scanned body parts helps medical practitioners make the right decision in lesser time. Image segmentation plays a vital role in automated diagnosis for the delineation of anatomical organs and anomalies.
Kumar Subbiahpillai Neelakantapillai   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Toward an “Ancient” Virtual World: Improvement Methods on X-ray CT Data Processing and Virtual Reconstruction of Fossil Skulls

open access: yesFrontiers in Earth Science, 2020
This article focuses on new virtual advances to solve technical problems usually encountered by paleontologists when using X-ray computed tomography (XCT), such as (i) the limited scanning envelope (i.e., field of view of CT systems/machines) to acquire ...
Alejandro Pérez-Ramos, Borja Figueirido
doaj   +1 more source

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