Results 81 to 90 of about 123,159 (318)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Rainbow Thresholds

SIAM Journal on Discrete Mathematics
We extend a recent breakthrough result relating expectation thresholds and actual thresholds to include some rainbow versions.
Tolson Bell, Alan M. Frieze, Trent G. Marbach   +2 more
openaire   +3 more sources

thresholding

, 2018
Example script to transform MAXENT models to binary presence-absence ...
Sytsma, Kenneth J., Givnish, Thomas J, Chloe P Drummond (8035715), Feist, Mary Ann, Li, Pan, Kenneth J. Sytsma (8033255), Alverson, William S., Pan Li (335711), Zaborsky, John G, Rose, Jeffrey R, Jeffrey R Rose (8035712), Bryan T Drew (8035706), Thomas J Givnish (8035718), Daniel Spalink (3263151), John G Zaborsky (8035709), Mary Ann Feist (8035694), William S. Alverson (8035697), Donald M. Waller (2916263), Kriebel, Ricardo, Pace, Matthew C, Drummond, Chloe P, Waller, Donald M., Kenneth M. Cameron (3317055), Ricardo Kriebel (3271884), Spalink, Daniel, Cameron, Kenneth M., Matthew C Pace (8035703), Drew, Bryan T   +27 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A novel thresholding based algorithm for detection of vertical root fracture in nonendodontically treated premolar teeth

Journal of Medical Signals and Sensors, 2016
In this paper, an efficient algorithm is proposed for detection of vertical root fractures (VRFs) in periapical (PA), and cone-beam computed tomography (CBCT) radiographs of nonendodontically treated premolar teeth.
Masume Johari, Farzad Esmaeili, Alireza Andalib, Shabnam Garjani, Hamidreza Saberkari   +4 more
doaj  

An Embedded Application for Degraded Text Recognition

EURASIP Journal on Advances in Signal Processing, 2005
This paper describes a mobile device which tries to give the blind or visually impaired access to text information. Three key technologies are required for this system: text detection, optical character recognition, and speech synthesis. Blind users and
Thillou Céline, Ferreira Silvio, Gosselin Bernard   +2 more
doaj   +1 more source

Toward an “Ancient” Virtual World: Improvement Methods on X-ray CT Data Processing and Virtual Reconstruction of Fossil Skulls

Frontiers in Earth Science, 2020
This article focuses on new virtual advances to solve technical problems usually encountered by paleontologists when using X-ray computed tomography (XCT), such as (i) the limited scanning envelope (i.e., field of view of CT systems/machines) to acquire ...
Alejandro Pérez-Ramos, Borja Figueirido
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

THORS: An Efficient Approach for Making Classifiers Cost-Sensitive

IEEE Access, 2019
In this paper, we propose an effective THresholding method based on the Order Statistic, called THORS, to convert an arbitrary scoring-type classifier, which can induce a continuous cumulative distribution function of the score, into a cost-sensitive one.
Ye Tian, Weiping Zhang
doaj   +1 more source

Comparative Study on Thresholding

, 2020
Criterion based thresholding algorithms are simple and effective for two-level thresholding. However, if a multilevel thresholding is needed, the computational complexity will exponentially increase and the performance may become unreliable.
Singh, K.C., Routray, S.K., Satapathy, Lalit Mohan, Dash, Bibhudatta   +3 more
core   +1 more source