Results 61 to 70 of about 123,159 (318)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Determination of Colles fracture risk index by X-ray images with the computer vision application

Bolʹ, Sustavy, Pozvonočnik
Background. Modelling a predictive risk index for Colles fractures using X-ray image analysis is a crucial application in orthopaedics since these fractures have essential health and economic burdens, particularly among the elderly. Previous research has
Wisam A. Hussein, Hussain J. AlKhatteib, Jawad K. Abbas   +2 more
doaj   +1 more source

Balancing with Thresholds

, 2017
The paper presents a general formal framework representing the role of balancing of values in interpretation of statutory rules. The model developed here is an extension of the model of teleological interpretation, where a given interpretive outcome is justified if it satisfies a given goal (or a set of goals).
Michal Araszkiewicz, Tomasz Zurek
openaire   +2 more sources

Threshold hypergraphs

Discrete Mathematics, 1985
Threshold graphs were introduced by \textit{V. Chvátal} and \textit{P. L. Hammer} [Ann. Discrete Math. 1, 145-162 (1977; Zbl 0384.90091)]. They gave three equivalent characterizations of these graphs. These characterizations were generalized for hypergraphs by \textit{M. Ch. Golumbic} [Combinatorics, Keszthely 1976, Colloq. Math.
Jan Reiterman, Vojtech Rödl, Edita Sinajová, Miroslav Tuma   +3 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Presidential Threshold Between the Threshold of Candidacy and Threshold of Electability [PDF]

JURNAL CITA HUKUM, 2018
Abstract. In judicial review on Article 9 of Law Number 42 of 2008 on The Election of President and Vice-President which regulates Presidential threshold, the Constitutional Court refused on the grounds that it is an open legal policy which mandated by Article 6 paragraph (5) of the 1945 Constitution that the administration of the election of President
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Thresholding approaches for estimating paraspinal muscle fat infiltration using T1‐ and T2‐weighted MRI: Comparative analysis using water–fat MRI

JOR Spine
Background Paraspinal muscle fat infiltration is associated with spinal degeneration and low back pain, however, quantifying muscle fat using clinical magnetic resonance imaging (MRI) techniques continues to be a challenge.
Jessica Ornowski, Lucas Dziesinski, Madeline Hess, Roland Krug, Maryse Fortin, Abel Torres‐Espin, Sharmila Majumdar, Valentina Pedoia, Noah B. Bonnheim, Jeannie F. Bailey   +9 more
doaj   +1 more source

Comparing background elimination approaches for processing of ancient Thai manuscipts on palm leaves

, 2009
The objective of the Preservation of Palm Leaf Manuscripts Project at Mahasarakham University at Thailand is to preserve and retrieve traditional knowledge from ancient manuscripts recorded on palm leaves. An essential task in the process is to recognize
Fung, C.C., Chun Che Fung, Rapeeporn Chamchong, Chamchong, R.   +3 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source