Results 91 to 100 of about 123,159 (318)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Thresholding RULES and iterative shrinkage/thresholding algorithm: A convergence study
, 2014 International audienceImaging inverse problems can be formulated as an optimization problem and solved thanks to algorithms such as forward-backward or ISTA (Iterative Shrinkage/Thresholding Algorithm) for which non smooth functionals with sparsity ...
Matthieu Kowalski, Kowalski, Matthieu
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Classification, Multiple Hypothesis Testing And Wavelet Thresholding Procedures With Applications
, 2006 [ITALIANO] Lo sviluppo delle metodologie statitistiche per l’analisi dati è generalmente collegato a progressi ottenuti in altri campi scientifici. Da un lato l’analisi statistica è spesso indirizzata a problemi reali, di conseguenza, il miglioramento ...
Cutillo, Luisa
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Comparative Study of Image Processing Techniques for Javanese Ancient Manuscripts Enhancement
IEEE AccessDigital preservation to preserve information in ancient manuscripts is often not optimal because of the object’s condition, which has degraded over time.
Imam Yuadi +3 more
doaj +1 more source
Thresholding Estimators for Linear Inverse Problems and Deconvolutions
, 2003 Thresholding algorithms in an orthonormal basis are studied to estimate noisy discrete signals degraded by a linear operator whose inverse is not bounded.
Deconvolutions +3 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Effects of the Ground Resolution and Thresholding on Crack Width Measurements
Sensors, 2018 When diagnosing the condition of a structure, it is necessary to measure the widths of any existing cracks in the structure. To ensure safety when relying on images of cracks, the selected imaging parameters and processing technology must be well ...
Hyunwoo Cho +2 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source