Results 31 to 40 of about 662,743 (219)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Stage-structured models for interacting wild and sterile mosquitoes

上海师范大学学报. 自然科学版, 2014
Using the sterile insect technique,in which sterile mosquitoes are released to reduce or eradicate the wild mosquito population,is an effective weapon to prevent transmission of mosquito-borne diseases.To study the impact of the sterile insect technique ...
Jia Li
doaj   +1 more source

Influence of Climate and Duration of Stream Water Presence on Rates of Litter Decomposition and Nutrient Dynamics in Temporary Streams and Surrounding Environments of Southwestern USA

Frontiers in Water, 2020
Ephemeral and intermittent streams are increasing with climate and land use changes, and alteration in stream water presence or flow duration will likely affect litter decomposition and nutrient dynamics in channel and riparian zones more than uplands ...
Kathleen A. Lohse, Erika L. Gallo, Erika L. Gallo, Thomas Meixner   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Precise Drought Threshold Monitoring in Winter Wheat Using the Unmanned Aerial Vehicle Thermal Method

Remote Sensing
Accurate monitoring of crop drought thresholds at different growth periods is crucial for drought monitoring. In this study, the canopy temperature (Tc) of winter wheat (‘Weilong 169’ variety) during the three main growth periods was extracted from high ...
Hongjie Liu, Wenlong Song, Juan Lv, Rongjie Gui, Yangjun Shi, Yizhu Lu, Mengyi Li, Long Chen, Xiuhua Chen   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Roles of Soil and Atmospheric Dryness on Terrestrial Vegetation Productivity in China ‐ Which Dominates at What Thresholds

Earth's Future
Low soil moisture (SM) and high vapor pressure deficit (VPD) can reduce vegetation productivity (gross primary productivity (GPP)) and weaken terrestrial carbon stock.
Tianzi Wang, Jingwen Zhang, Zejun Li, Kairong Lin, Wang Zhou, Genghong Wu, Ming Pan, Xiaohong Chen   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source