Results 41 to 50 of about 662,743 (219)

The Effects of Temperature on the Development and Survival of Bathycoelia distincta (Hemiptera: Pentatomidae), a Significant Pest of Macadamia in South Africa

open access: yesInsects
Temperature is the most influential condition affecting insect development and population dynamics. Understanding its impact and other important factors, such as diet, could provide fine-scale predictions of species abundance and distribution in space ...
Mulalo M. Muluvhahothe   +2 more
doaj   +1 more source

Changes in Precipitation and Drought Extremes over the Past Half Century in China

open access: yesAtmosphere, 2019
Changes in climate extremes have become a hot issue in the research field of climate change recently. Many studies have reported that climate extremes have occurred more frequently and with increasing intensity in recent decades.
Min Liu   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On Approaches to Assessing Contribution of Russian Universities in the Implementation of National Projects

open access: yesВысшее образование в России, 2019
The article provides a brief review of the literature related to the analysis of approachesto assessing the effectiveness of the universities of the country.
I. V. Arzhanova   +2 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Integrating water depth to predict the threshold of collapse and recovery of submerged macrophytes for lakes with large depth gradients

open access: yesFrontiers in Plant Science
IntroductionThe nutrient threshold of collapse and recovery of submerged macrophytes have been widely reported for shallow lakes. However, understanding the threshold variation for lakes with water depth (Z) gradients remains limited.MethodsIn this study,
Yexin Yu   +9 more
doaj   +1 more source

Detecting the Dynamics of Urban Growth in Africa Using DMSP/OLS Nighttime Light Data

open access: yesLand, 2020
Africa has been experiencing a rapid urbanization process, which may lead to an increase in unsustainable land use and urban poverty. Assessing the spatiotemporal characteristics of urbanization dynamics is especially important and needed for the ...
Shengnan Jiang   +7 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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