Results 61 to 70 of about 51,793 (265)

Optimization of Magnetic Milli‐Spinner for Robotic Endovascular Intervention

Advanced Robotics Research, EarlyView.
This work presents the design optimization of a multifunctional magnetic milli‐spinner for high‐speed propulsion and efficient clot debulking. The optimized design achieves an ultrafast swimming velocity of 55 cm/s (≈175 body lengths/s) in saline water, enabling stable upstream swimming against strong physiological flows and establishing magnetic milli‐
Lu Lu, Luca Higgins, Jack Bernardo, Ruike Renee Zhao   +3 more
wiley   +1 more source

Developments in mechanical thrombectomy devices for the treatment of acute ischemic stroke

, 2016
Several recent prospective randomized controlled trials of endovascular stroke therapy using latest generation thrombectomy devices, so called stent-retrievers, have shown significantly improved clinical outcome compared to the standard treatment with ...
Gralla, Jan, Mordasini, Pasquale
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Post-operative neutrophil-to-lymphocyte ratio and outcome after thrombectomy in acute ischemic stroke

Frontiers in Neurology, 2022
BackgroundNeutrophil to lymphocyte ratio (NLR) is a novel inflammatory marker to predict adverse cardiovascular events. However, there is a lack of data on hemorrhagic transformation (HT) and neurological outcome after mechanical thrombectomy in acute ...
Shen-Jie Li, Shan-Shan Cao, Pei-Sheng Huang, Xin Nie, Yang Fu, Jian-Ren Liu   +5 more
doaj   +1 more source

The Impact of Early Postoperative Blood Pressure Variability and Hypertension Status on 90‐Day Functional Outcomes in Acute Ischemic Stroke due to Large Vessel Occlusion Patients Treated With Mechanical Thrombectomy

AGING MEDICINE, EarlyView.
Early postoperative blood pressure variability independently predicts poor 90‐day functional outcomes in AIS‐LVO patients after mechanical thrombectomy, with the adverse effect amplified in those with pre‐existing hypertension. Maintaining stable blood pressure in the early postoperative period may improve recovery in this high‐risk population ABSTRACT
Yunpeng Liu, Yiqi Liu, Zeping Jin, Jumei Huang, Yang Wang   +4 more
wiley   +1 more source

Case Series Utilizing a Novel Rotational Mechanical Thrombectomy Device for the Treatment of Thrombosed Arteriovenous Grafts in Thailand

Journal of Health Science and Medical Research (JHSMR)
Endovascular treatment of thrombosed hemodialysis access is a standard option for restoring flow. Standard treatments, including pharmacomechanical thrombolysis, mechanical thrombectomy, or a combination of therapies, have been commonly used.
Keerati Hongsakul, Thanakorn Phothong, Sorracha Rookkapan, Surasit Akkakrisee, Phurich Janjindamai, Boonprasit Kritpracha, Ussanee Boonsrirat, Pete Stibbs   +7 more
doaj   +1 more source

A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy

Advanced Intelligent Systems, EarlyView.
This article presents a novel magnetic aspiration catheter (MAC) that can be both actively steered and undergo distal‐end expansion via externally applied magnetic fields. The MAC facilitates precise branch selection and enhances clot engagement by improving endovascular navigation and aspiration efficiency. Phantom experiments validate its feasibility
Hakjoon Lee, Xiao Dong, Dong‐in Kim, A. M. Masum Bulbul Chowdhury, Nader Latifi Gharamaleki, Jin‐young Kim, Sung Won Youn, Hongsoo Choi   +7 more
wiley   +1 more source

Analysis of the efficacy of mechanical thrombectomy in acute progressive ischemic stroke with large vessel occlusion in the anterior circulation

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the efficacy and safety of mechanical thrombectomy in patients with acute progressive ischemic stroke with large vessel occlusion in the anterior circulation.
HAN Ning, ZHAO Yan, MA Liang, WANG He⁃bo, XU Guo⁃dong   +4 more
doaj   +1 more source

Intra-Arterial Thrombolysis is Associated with Delayed Reperfusion of Remaining Vessel Occlusions following Incomplete Thrombectomy.

, 2023
BACKGROUND AND PURPOSE Intra-arterial thrombolytics may be used to treat distal vessel occlusions, which cause incomplete reperfusion following mechanical thrombectomy.
Seiffge, D J, Piechowiak, E I, Serrallach, B L, Pilgram-Pastor, S, Mujanovic, A, Gralla, J, Dobrocky, T, Fischer, U, Kurmann, C C, Windecker, D, Beyeler, M, Arnold, M, Kaesmacher, Johannes, Meinel, T R, Grunder, L   +14 more
core   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source