Results 71 to 80 of about 675 (163)

The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy

American Journal of Medical Genetics Part A, Volume 194, Issue 4, April 2024.
Abstract Germline pathogenic variants in the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway are the molecular cause of RASopathies, a group of clinically overlapping genetic syndromes. RASopathies constitute a wide clinical spectrum characterized by distinct facial features, short stature, predisposition to cancer, and variable anomalies
Elizabeth I. Pierpont, Anton M. Bennett, Lisa Schoyer, Beth Stronach, April Anschutz, Sarah C. Borrie, Benjamin Briggs, Emma Burkitt‐Wright, Pau Castel, Ion C. Cirstea, Fieke Draaisma, Michelle Ellis, Vanessa S. Fear, Megan N. Frone, Elisabetta Flex, Bruce D. Gelb, Tamar Green, Karen W. Gripp, Sattar Khoshkhoo, Mark W. Kieran, Karolin Kleemann, Bonita P. Klein‐Tasman, Maria I. Kontaridis, Paul Kruszka, Chiara Leoni, Clifford Z. Liu, Nadia Merchant, Pilar L. Magoulas, Christopher Moertel, Carlos E. Prada, Katherine A. Rauen, Renée Roelofs, Rodrigue Rossignol, Christine Sevilla, Gigi Sevilla, Ryan Sheedy, Elliot Stieglitz, Daochun Sun, Dagmar Tiemens, Forest White, Ellen Wingbermühle, Cordula Wolf, Martin Zenker, Gregor Andelfinger   +43 more
wiley   +1 more source

Thrombelastography and tromboelastometry in assessing coagulopathy in trauma

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2009
Death due to trauma is the leading cause of lost life years worldwide, with haemorrhage being responsible for 30-40% of trauma mortality and accounting for almost 50% of the deaths the initial 24 h.
Bochsen Louise, Stissing Trine, Johansson Pär I, Ostrowski Sisse R   +3 more
doaj   +1 more source

Prevention of postoperative bleeding after complex pediatric cardiac surgery by early administration of fibrinogen, prothrombin complex and platelets: a prospective observational study

BMC Anesthesiology, 2020
Background Postoperative bleeding is a major problem in children undergoing complex pediatric cardiac surgery. The primary aim of this prospective observational study was to evaluate the effect of an institutional approach consisting of early preventive ...
Nils Dennhardt, Robert Sümpelmann, Alexander Horke, Oliver Keil, Katja Nickel, Sebastian Heiderich, Dietmar Boethig, Christiane E. Beck   +7 more
doaj   +1 more source

State of the art, trends, hotspots, and prospects of injection materials for controlling bleeding

International Wound Journal, Volume 21, Issue 1, January 2024.
Abstract Traumatic haemorrhage is a prevalent clinical condition, and effective and timely haemostasis is crucial for the preservation of patients' lives. In recent years, injectable hemostatic materials have gained significant attention due to their excellent hemostatic efficacy, biocompatibility, and biodegradability, making them widely applied in ...
Changsheng Feng, Liang Yang
wiley   +1 more source

Dual Hemostatic Disruption in Light Chain Amyloidosis: A Comparative Analysis of Platelet Adhesion and Thrombin Generation [PDF]

Documenta Haematologica
Amyloidosis is a systemic disorder, characterised by the deposition of misfolded proteins in the extracellular matrix. Primary amyloidosis (AL) is a subtype in which immunoglobulin light chains, undergo the same misfolding and deposition process and are ...
Mihai Emanuel HIMCINSCHI, Delia Codruta POPA, Sorina Nicoleta BADELITA, Mihaela UTA, Daniel CORIU, Andrei ANGHEL   +5 more
doaj   +1 more source

An overview of thrombelastography research

, 2021
Introducción:La tromboelastografía (TEG) es un método para valorar las características de la formación y destrucción del coágulo. Una variedad de aplicaciones han sido sugeridas en la literatura.Objetivo:Proporcionar un resumen acerca del conocimiento ...
Muñoz, Luis A., Cortés, Cristian C., Pabón, Germán A., Arévalo, Jimmy J., Sulaiman, Othman, Reyes, Luis E.   +5 more
core  

A novel method of thrombelastograph analysis aids assessment of antiplatelet therapy in percutaneous coronary intervention.

, 2010
MD (Research)Background A near-patient test of responses to antiplatelet therapy would be of great value in percutaneous coronary intervention (PCI). However, at present, there are no widely accepted tests and varied definitions of “resistance”.
Hobson, Alex
core  

Rattlesnake Roundup: Point-of-Care Thrombelastographic Methods Define the Molecular Impacts on Coagulation of Crotalus Venom Toxins In Vitro and In Vivo

Toxins
A malalignment between rattlesnake-envenomed patients’ degree of compromised coagulation and the data generated by standard hematological determinations generated with blood samples anticoagulated with calcium (Ca) chelating agents is almost certain ...
Vance G. Nielsen
doaj   +1 more source

The use of viscoelastic haemostatic assays in goal-directing treatment with allogeneic blood products – A systematic review and meta-analysis

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2017
Background Management of the critically bleeding patient can be encountered in many medical and surgical settings. Common for these patients is a high risk of dying from exsanguination secondary to developing coagulopathy.
Mathilde Fahrendorff, Roberto S. Oliveri, Pär I. Johansson   +2 more
doaj   +1 more source

Studying Hypercoagulability in Hip Fracture Patients as Determined by Thrombelastography

, 2020
Hip fractures are the most devastating manifestation of osteoporosis with high venous thromboembolic (VTE) rates reported following surgery. Currently, there is no guideline consensus on the optimal duration of pharmacologic thromboprophylaxis or ...
You, Daniel Zheng
core   +1 more source