Results 181 to 190 of about 162,133 (299)

Miniaturization of Aptasensors in Organic Electrochemical Transistors for Sensitivity Enhancement. [PDF]

Anal Chem
Asyuda A, Odunbaku RT, Striethorst LJL, Barbosa HFP, Schander A, Kumar R, Gakhar DEN, Bornemann S, Armstrong RE, Lüssem B.   +9 more
europepmc   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

A miniaturized chemiluminescent thrombin generation assay to assess the effect of APCC in persons with hemophilia A with inhibitors: an observational study. [PDF]

Res Pract Thromb Haemost
Bavinck AP, Steeghs TJ, van Engelshoven L, Coolen NMM, van de Ridder CJ, Baran B, Windyga J, Blijlevens NMA, Schols SEM, van 't Veer C, van Heerde WL.   +10 more
europepmc   +1 more source

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

Cardiometabolic Protein Profile Changes During Gender‐Affirming Hormone Therapy: A Prospective Clinical Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Cardiovascular disease (CVD) risk is elevated in transgender individuals during gender‐affirming hormone therapy (GAHT) with expected different mechanisms between T‐ and E2‐based GAHT. We investigated prospective changes in cardiometabolic proteins relating to complement, inflammation, and transport during GAHT.
Emilie Bukh Madsen, Louise Lehmann Christensen, Sara Ravn Bach, Louise Skøttrup Christiansen, Mathilde Kamp Nørlund, Tine Taulbjerg Kristensen, Guy T'Sjoen, Anne Pernille Hermann, Camilla Viola Buskbjerg Palm, Jan Frystyk, Marianne Skovsager Andersen, Martin Overgaard, Dorte Glintborg   +12 more
wiley   +1 more source

Thrombin concentration shapes endothelial extracellular vesicle profiles with divergent inflammatory functions. [PDF]

Blood Adv
Chatterjee M, Keshava S, Dhara P, Kavadipula P, Mukherjee T, Paul S, Chatterjee A, Maitra A, Uddandrao VVS, Das K, Rao LVM.   +10 more
europepmc   +1 more source

Platelet concentrates in sinus augmentation: The impact of platelet dose and biological characteristics—A systematic review and meta‐analysis

European Journal of Oral Sciences, EarlyView.
Abstract This systematic review investigated the osteogenic effects of platelet concentrate (PRF/PRP) when combined with non‐autogenous graft materials in sinus lift procedures. Key characteristics assessed included platelet concentration, total platelet dose, leukocyte content, and fibrin‐network structure.
Olav Kansgar Straum, Hans Thomas Brox, Juliane Hesse, Andreas Jörn Schmalfuss, Erlend Bugge   +4 more
wiley   +1 more source

Treatment approaches for equine subchondral lucencies: Clinical considerations and therapeutic decision‐making

Equine Veterinary Education, EarlyView.
Summary Subchondral lucencies, also referred to as subchondral cystic lesions or osseous cyst‐like lesions, are radiographically identifiable defects of subchondral bone that remain an important cause of lameness and reduced athletic performance in horses.
C. Salazar‐Latorre, R. Salcedo‐Jiménez, M. Masri‐Daba   +2 more
wiley   +1 more source

Tissue Factor/Factor XIa Dual-activated Thrombin Generation is Able to Reliably Measure Thrombin Generation at All Hemophilia A Disease Severities. [PDF]

TH Open
van de Berg TW, Heinzmann A, Thomassen S, Schols SEM, Heubel-Moenen FCJI, van Es N, Rosendaal FR, Gouw S, Hackeng TM, Beckers EAM.   +9 more
europepmc   +1 more source

Complement–Eosinophil Crosstalk Links Complement Activation to Fibrin Deposition in Eosinophilic Chronic Rhinosinusitis

Allergy, EarlyView.
Ryo Hasegawa, Shigeharu Ueki, Misaki Arima, Shohei Nishiyama, Keinosuke Hizuka, Kohei Tatsumi, Ayako Sawai, Anna Shimizu, Yuki Sonoda, Eiichi Kato, Masanori Kidoguchi, Masafumi Sakashita, Yohei Sato, Atsushi Kato, Bruce K. Tan, Robert C. Kern, Robert P. Schleimer, Shigeharu Fujieda, Yoshimasa Imoto   +18 more
wiley   +1 more source