Results 71 to 80 of about 21,457 (218)
Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation
ACR Open Rheumatology, Volume 8, Issue 6, June 2026.Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley +1 more source
Essential thrombocythemia presenting as digital ischemia
, 2017 Essential thrombocythemia is a myeloproliferative disease and is characterized by increased production of platelet and increased megakaryocytes in the bone marrow.
Md. Abdur Rahim +5 more
core +2 more sources
Cancer, Volume 132, Issue 11, 1 June 2026.Abstract Background Mutations in cytokine receptor and JAK/STAT; Cy‐JAK/STAT) signaling genes drive myeloproliferative neoplasms (MPNs) but remain incompletely characterized in acute myeloid leukemia (AML). The authors evaluated the prevalence, clinical presentation, and prognostic significance of Cy‐JAK/STAT pathway mutations in patients with AML and ...
Moath Albliwi +22 more
wiley +1 more source
Essential Thrombocythemia in a Cat
Journal of Veterinary Internal Medicine, 1990 Abstarct The diagnosis of essential thrombocythemia in a cat was made by fulfilling the five applicable criteria set forth by the Polycythemia Vera Study Group forusein humans. The criteria were 1) a platelet count persistently above 600,000/μL, 2) a normal initial hematocrit that did not rise in response to iron therapy, 3) normal ...
A S, Hammer +3 more
openaire +2 more sources
BCR/ABL positive thrombocythemia: a diagnostic dilemma
, 2017 Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients.
Anjum Parvez +3 more
core +1 more source
Haematologica, 2009 Background Hereditary thrombocythemia is a rare disease characterized by increased megakaryopoiesis and overproduction of platelets. Germ line mutations have been identified in the genes for thrombopoietin (THPO) and its receptor, MPL.
Kun Liu +9 more
doaj +1 more source
Open Access Emergency Medicine, 2016 Marvinia Charles, Romy Fontoura, Gregory Sugalski Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA Abstract: Thrombocytosis is frequently encountered as an incidental laboratory finding since isolated thrombocytosis ...
Charles M, Fontoura R, Sugalski G
doaj
Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations
Haematologica, 2014 Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing ...
Hajnalka Andrikovics +13 more
doaj +1 more source
What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson +5 more
wiley +1 more source