Results 131 to 140 of about 190,265 (268)

Altered T cell immune profile and its prognostic implications in children with portal hypertension: A pilot study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Immune dysregulation in paediatric portal hypertension (PHT) is poorly understood. We aimed to characterise T cell phenotype and function and circulating immune mediators in children with PHT according to disease aetiology. Methods Forty‐four children with PHT (27 chronic liver disease [CLD]‐related and 17 portal vein thrombosis ...
Tengfei Si, Huihong Yu, Bethany Tucker, Fabiola Di Dato, Qing Shao, Xuan Luo, Cody Chan, Pauline Kane, Dylan Lewis, Eirini Kyrana, Yun Ma, Tassos Grammatikopoulos   +11 more
wiley   +1 more source

Biomarkers of native liver survival and portal hypertension in biliary atresia

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective To evaluate the prognostic value of noninvasive markers Aspartate Aminotransferase to Platelet Ratio Index (APRi) and Infantile Biliary Atresia Liver Fibrosis score (iBALF), as well as the histological Ishak fibrosis score, as predictors of native liver survival (NLS) and portal hypertension (PH) in children with biliary atresia (BA)
Karyne Sumico de Lima Uyeno Jordão, Larissa Bastos Eloy da Costa, Maria Ângela Bellomo‐Brandão   +2 more
wiley   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

JPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder, Naomi Laventhal, Raja Rabah, Jacqueline Meadow   +3 more
wiley   +1 more source

Severe Thrombocytopenia Induced by Re-Exposure to Piperacillin/Tazobactam: A Case Report in Critically Ill Patient With COVID-19. [PDF]

Clin Case Rep
Alharthi AF, Alkathiri MA, Alomeir O, Al Harbi S, Aljuhani O, Alhaidal HA, Al Sulaiman K.   +6 more
europepmc   +1 more source

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

JPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi, Rachel Schenker, Nick Shillingford, George Yanni   +3 more
wiley   +1 more source

Thrombocytopenia Warrants Clinical Attention in Hospitalized Patients with Sarcoidosis. [PDF]

J Clin Med
Dumanis G, Ofek T, Gubbay A, Tal C, Moshkovich I, Klegar N, Ohayon PA, Tennenhaus N, Segal G, Farkash Y, Bendersky D, Tzibin M, Kassif Lerner R.   +12 more
europepmc   +1 more source

Use of single‐use ultra‐slim endoscopes for evaluation of pediatric esophageal varices: A pilot feasibility study

JPGN Reports, EarlyView.
ABSTRACT Esophageal varices (EV) need monitoring in patients with portal hypertension. In 2022, a single‐use ultra‐slim (3.5 mm) gastroscope was approved for use in children and adults. This study evaluated if an ultra‐slim gastroscope could evaluate, grade, and corroborate the presence of EV in sedated pediatric patients as compared to standard oral ...
Vishruti Patel, Evan Greenhall, Eric Dybbro, Sheetal Wadera, Joel A. Friedlander, Shauna Schroeder, Paul Tran   +6 more
wiley   +1 more source

Severe constipation‐associated postprandial abdominal pain in a pregnant native‐liver biliary atresia survivor after Kasai portoenterostomy: A case report

JPGN Reports, EarlyView.
ABSTRACT An 18‐year‐old woman with congenital biliary atresia status post Kasai portoenterostomy and magnetic resonance imaging‐reported chronic liver disease presented at 32 weeks’ gestation with 6 weeks of worsening postprandial epigastric/right upper quadrant pain, nausea, and poor oral intake.
Akram Alnounou, Ajay Katwala, Mohammad Alabbas, Bisher Sawaf, Arghyadeep Ganguly, EzzElDien A. Ibrahim, Fnu Vikash   +6 more
wiley   +1 more source

Essential fatty acid status in tube‐fed children with medical complexity: A cross‐sectional study

JPGN Reports, EarlyView.
Abstract Objective Essential fatty acid deficiency (EFAD) occurs when daily nutrition provisions lack sufficient linoleic acid or a‐linolenic acid. Signs, symptoms, and sequelae are nonspecific but impact health and quality of life. The objective of this study was to determine the incidence of EFAD among pediatric patients with chronic, complex ...
Ashley B. Prusakov, Marissa L. Testa, Madelyn Kelley, Vedat O. Yildiz, Garey Noritz, Ethan A. Mezoff   +5 more
wiley   +1 more source

Markedly Elevated Serum IgE in a Patient With Thrombocytopenia and a TUBA8 Variant of Uncertain Significance: A Case Report. [PDF]

Case Reports Immunol
Nabavizadeh SH, Askarisarvestani A, Esmaeilbeig M, Shahriari M.   +3 more
europepmc   +1 more source