Results 161 to 170 of about 190,265 (268)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Fetal Intracranial Hemorrhage: What to Tell Expecting Parents?

Prenatal Diagnosis, EarlyView.
ABSTRACT Fetal intracranial hemorrhage (ICH) is a rare but serious prenatal diagnosis, and counseling affected families remains challenging. In this narrative review, we summarize current evidence on the classification, epidemiology, etiology, diagnosis and neurodevelopmental outcomes of fetal ICH, with a primary focus on intraventricular hemorrhage ...
Shiri Shinar, Yada Kunpalin, Elka Miller
wiley   +1 more source

Molecular overlap between primary immune thrombocytopenia and inherited platelet disorders: A pediatric case report with a novel heterozygous ITGB3 variant identified by next-generation sequencing. [PDF]

Ther Adv Hematol
Duarte Rodríguez FD, González Figueredo ÓE, Gasca AC.   +2 more
europepmc   +1 more source

Biological Specificities of Fetal Anemia Induced by Parvovirus B19 Infection

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To describe the biological fetal parameters in cases of severe anemia induced by parvovirus B19 (B19V) infection. Method A retrospective single center study was conducted including cases of fetal anemia due to B19V receiving in utero transfusion (IUT) from January 2011 to May 2024.
Anaïs Dugas, Paul Maurice, Pierre Olivo‐Marin, Mariam Chelghaf, Loriane Franchinard, Ferdinand Dhombres, Lucie Guilbaud, Laurence Berard, Agnès Mailloux, Jean‐Marie Jouannic   +9 more
wiley   +1 more source

Early postnatal complications in small-for-gestational-age infants by gestational age and SGA severity: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Fuwa K, Watanabe Y, Sato Y, Go H, Hara K, Aoki R, Hijikata M, Tanabe S, Aoki M, Okahashi A, Nagano N, Morioka I.   +11 more
europepmc   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Efficacy and safety of eltrombopag in the treatment of cancer therapy-induced thrombocytopenia: a large-scale, multicenter, retrospective study in China. [PDF]

Blood Sci
Ding B, Chen Y, Huang H, Lin Y, Li L, Zheng L, Zhang H, Zhou H.   +7 more
europepmc   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Bortezomib‐based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single‐center retrospective study

Pediatric Investigation, EarlyView.
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao, Jian Wang, Liping Que, Dunhua Zhou, Jianpei Fang, Luhong Xu   +5 more
wiley   +1 more source

Case Report: Prolonged thrombocytopenia after chemotherapy in solid tumors requiring long-term thrombopoietin receptor agonist support: a five-patient case series. [PDF]

Front Oncol
Wang S, Yu Y, Zhang L, Liu Q.
europepmc   +1 more source