Estimated impact of model‐guided venous thromboembolism prophylaxis versus real‐world practice
Abstract Background The American Society of Hematology (ASH) recommends assessing venous thromboembolism (VTE) and major bleeding risk to optimize pharmacological VTE prophylaxis for medical inpatients. However, the clinical utility of model‐guided approaches remains unknown.
Benjamin G Mittman, Michael B. Rothberg
wiley +1 more source
Recurrent severe thrombocytopenia induced by anti-HER2 therapy in a breast cancer patient with an underlying immune disorder: a case report and literature review. [PDF]
Wang B, Chen L, Tang Q.
europepmc +1 more source
The “5L” framework of diagnostic reasoning: A stepwise scaffold to support clinician educators
Abstract Diagnostic reasoning (DR) is a core clinical skill, yet its teaching remains variable. We introduce the “5L” framework as a bedside teaching scaffold that gives educators and learners a shared, stepwise set of prompts for DR during individual encounters. By asking, “What's Lethal? What's Likely? What's Logical? What's Lurking?
Olivia Brumfield +3 more
wiley +1 more source
Very-low-dose decitabine and rhTPO for thrombocytopenia in lower-risk myelodysplastic syndrome. [PDF]
Gao Z +17 more
europepmc +1 more source
Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He +11 more
wiley +1 more source
From Epistaxis to a Platelet Count of Four: A Rare Presentation of Teicoplanin-Induced Thrombocytopenia. [PDF]
Shrestha A, Jain U, Mathew A, Ha K.
europepmc +1 more source
Esophageal stenosis secondary to severe loxoscelism: A case report
ABSTRACT Loxoscelism is a public health issue in tropical countries, particularly in Brazil. It can affect children of all ages and may lead to severe and irreversible injuries. We report the case of an infant who suffered a severe loxoscelism accident in the cervical region, progressing to esophageal stricture requiring multiple dilations. Fortunately,
Lucas Rocha Alvarenga +3 more
wiley +1 more source
Successful Haplo-Hematopoietic Stem Cell Transplantation for Juvenile Myelomonocytic Leukemia in a Child With Underlying Thrombocytopenia-Absent Radius Syndrome: A Unique Case. [PDF]
Sharidah SA +3 more
europepmc +1 more source
Abstract Pediatric patients with CD19+ acute lymphoblastic leukemia (ALL) undergoing chimeric antigen receptor T‐cell (CAR‐T) therapy frequently experience gastrointestinal (GI) complications. A retrospective study analyzed 13 patients (median age: 8 years) treated between January 2020 and January 2024.
Judith Raya Muñoz +8 more
wiley +1 more source

