Results 191 to 200 of about 288,284 (303)

Waldenström Macroglobulinemia Diagnosed by Ultrasonography‐Guided Biopsy of the Right Perinephric Tumor

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Waldenström macroglobulinemia is a low‐grade B‐cell lymphoma characterized by lymphoplasmacytic lymphoma infiltration of the bone marrow and immunoglobulin M (IgM) protein. Case Presentation An 80s‐year‐old male presented to our hospital with chief complaints of weight loss and general fatigue.
Shingo Morinaga   +9 more
wiley   +1 more source

Leuprorelin‐Induced Thrombocytopenia Successfully Treated With Surgical Resection of the Injection Site

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Drug‐induced thrombocytopenia (DITP) can be caused by many kinds of drugs. Its treatment generally involves discontinuation of the responsible drug. Case Presentation A 70‐year‐old man received a subcutaneous injection of long‐acting (24‐week) leuprorelin depot as androgen deprivation therapy for prostate cancer.
Ryota Mori   +18 more
wiley   +1 more source

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

open access: yesiMetaOmics, EarlyView.
This study investigates the risk of thrombotic microangiopathy (TMA) induced by vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) inhibitors in cancer therapy. Using data from the FDA Adverse Event Reporting System (FAERS), the WHO Global Database for Adverse Drug Reactions (Vigibase), and The Cancer ...
Aimin Jiang   +7 more
wiley   +1 more source

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

SARS‐CoV‐2 infection of companion animals in Egypt and its risk of spillover

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 13-24, January 2023., 2023
Graphical abstract depicts SARS‐CoV‐2 spillover in humans and their pet animals with common symptoms. Besides, it illustrates number of SARS‐CoV‐2‐infected cats and dogs with severity of respiratory signs. Abstract Background Reverse zoonoses occur because of interactions between humans and animals.
Mervat E. Hamdy   +6 more
wiley   +1 more source

Splenectomy for thrombocytopenia in chronic granulocytic leukemia [PDF]

open access: bronze, 1972
George P. Canellos   +2 more
openalex   +1 more source

Tirofiban-Induced Profound Thrombocytopenia: A Case Report. [PDF]

open access: yesCureus
Al Achkar Z   +3 more
europepmc   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Markers for internal neoplasia in the horse

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source

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