Results 241 to 250 of about 288,284 (303)

A Novel Series of Synthetic Heparin‐Mimetics–Itaconic Acid‐Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

Macromolecular Bioscience, EarlyView.
Heparin is postulated to possess antitumor properties‐ beyond its anticoagulative activities in oncology, but disclosure of targeted activities is complicated by heparins structural variabilities as natural glycosaminoglycans. Here, synthetic noncarbohydrate polymers are presented with tuneable structures as heparin mimetics in in‐vitro‐approaches for ...
Katrin Nekipelov, Abdullah Al Nahain, Sven Otto, Yongbin Xu, Jin‐Ping Li, Natasha Letunica, Simon Collett, Chantal Attard, Paul Monagle, George Vamvounis, John Tsanaktsidis, Vito Ferro, Gerd Bendas   +12 more
wiley   +1 more source

Measurement of ploidy distribution in megakaryocyte colonies obtained from culture: with studies of the effects of thrombocytopenia [PDF]

, 1981
J Levin, FC Levin, D. G. Penington, D Metcalf   +3 more
openalex   +1 more source

The prevalence of thrombocytopenia among pregnant women in Ethiopia: a systematic review and meta-analysis. [PDF]

BMC Pregnancy Childbirth
Jaldo MM, Jena BH, Bawore SG.
europepmc   +1 more source

Automatic bone marrow segmentation for precise [177Lu]Lu‐PSMA‐617 dosimetry

Medical Physics, EarlyView.
Abstract Background Bone marrow (BM) is the dominant dose‐limiting organ in [177Lu]Lu‐PSMA‐617 therapy for patients with metastasized castration resistant prostate cancer, where BM dosimetry is challenging due to segmentation. Purpose We aim to develop an automatic image‐based segmentation method on peri‐therapeutic sequential [177Lu]Lu‐PSMA‐617 images
Zhonglin Lu, Jiaxi Hu, Gefei Chen, Han Jiang, Cheng‐Ting Shih, Ali Afshar‐Oromieh, Axel Rominger, Kuangyu Shi, Greta S. P. Mok   +8 more
wiley   +1 more source

Associations of preoperative hematocrit and platelet count with morbidity after pathologic fracture fixation. [PDF]

J Bone Oncol
Sayed ME, Zastrow R, Youssef S, Levin AS.   +3 more
europepmc   +1 more source

A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric and Young Adult Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Developing targeted therapies with manageable toxicities remains a high priority for pediatric cancer. We sought to determine the recommended Phase 2 dose (RP2D) and evaluate the antitumor activity of lenvatinib+everolimus in children/young adults with select recurrent/refractory solid tumors.
Filemon S. Dela Cruz, Elizabeth Fox, Steven G. DuBois, Gregory K. Friedman, James M. Croop, AeRang Kim, Daniel A. Morgenstern, Frank M. Balis, Margaret E. Macy, Joseph G. Pressey, Tanya Watt, Julie I. Krystal, Kieuhoa T. Vo, Rajen Mody, Theodore W. Laetsch, Brenda J. Weigel, Karen O'Hara, Cixin S. He, Jagadeesh Aluri, Chinyere E. Okpara, Julia L. Glade Bender   +20 more
wiley   +1 more source

Extracorporeal Circulation in a Patient with Heparin-induced Thrombocytopenia [PDF]

, 1985
Jill P. Smith, Joseph T. Walls, Mary S. Muscato, Eric S. McCord, Eugene R. Worth, Jack J. Curtis, Donald Silver   +6 more
openalex   +1 more source

Low molecular weight heparin-induced thrombocytopenia management during hemodialysis and cardiac surgery: a case report and literature review. [PDF]

JA Clin Rep
Takada S, Suzuki S, Tamura T.
europepmc   +1 more source

Venetoclax Alone or in Combination With Chemotherapy in Paediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Myeloid Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Venetoclax is a potent, oral BCL‐2 inhibitor approved as combination therapy for the treatment of adults with newly diagnosed acute myeloid leukaemia (AML) who are ineligible for intensive chemotherapy. This study evaluated the safety and preliminary efficacy of venetoclax alone or combined with chemotherapy in paediatric and ...
Seth E. Karol, Seong L. Khaw, C. Michel Zwaan, Andre Baruchel, Henrique Bittencourt, Todd M. Cooper, Christian Flotho, Christopher Fraser, Christopher J. Forlenza, Kelly C. Goldsmith, Margaret E. Macy, Daniel A. Morgenstern, Maureen M. O'Brien, Arnaud Petit, David S. Ziegler, Dirk Reinhardt, Joseph T. Opferman, Jeffrey E. Rubnitz, Maika Onishi, Diana R. Dunshee, Fengjiao Dunbar, Deeksha Vishwamitra, Jeremy A. Ross, Xin Chen, Kristina Unnebrink, Maja Kammerlander, Ahmed Hamed Salem, Tammy L. Palenski, Gauri Sunkersett, Andrew E. Place   +29 more
wiley   +1 more source

Utility and Safety of Romiplostim as an Alternative to Platelet Transfusion for Neonates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Thrombocytopenia is a common challenge in the neonatal intensive care unit, traditionally managed with platelet transfusions. However, transfusions are associated with significant risks, including increased mortality and neurodevelopmental impairment.
Rachel N. Zeno, Sara Awad, Harry Lesmana
wiley   +1 more source