Results 311 to 320 of about 411,515 (387)

Use and Effects of Eltrombopag in Pregnant Woman With Difficult-to-Treat Idiopathic Thrombocytopenic Purpura (ITP). [PDF]

Case Rep Hematol
de Farias GCF, de Sá GT, Mercadante RV, Stefanello B, Francisco RPV, Igai AMK.   +5 more
europepmc   +1 more source

Postmarketing Assessment of Antibody–Drug Conjugates: Proof‐of‐Concept Using Model‐Based Meta‐Analysis and a Clinical Utility Index Approach

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Antibody–drug conjugates (ADCs) are a promising class of targeted cancer therapies. However, they need careful dose optimization to maximize effectiveness and minimize side effects. Sometimes, safety issues may only become apparent after approval, so ongoing evaluation is important.
Innocent Gerald Asiimwe, Nour Chtiba, Samer Mouksassi, Goonaseelan (Colin) Pillai, Raimund M. Peter, Eunice Yuen, Venkatesh Pilla Reddy   +6 more
wiley   +1 more source

Evidence of Vertical Dengue Transmission: A Case of Fever in a 4-Day-Old Neonate. [PDF]

Am J Case Rep
Lubis BM, Syafutri RD, Matondang HTA, Sari D.   +3 more
europepmc   +1 more source

Discontinuation of the Clozapine Risk Evaluation and Mitigation Strategy and Implications in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Charles Palmer, Alexander McClanahan, Federico Rodriguez‐Porcel   +2 more
wiley   +1 more source

Population Pharmacokinetics and Exposure–Response Relationships of Maribavir in Transplant Recipients With First Episode or Refractory Cytomegalovirus

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Maribavir's anti‐cytomegalovirus (CMV) activity and favorable safety/tolerability profile is a welcomed addition to the CMV treatment armamentarium. To further characterize pharmacokinetic (PK) and exposure–response relationships of maribavir in transplant recipients with CMV, a population PK model was updated with data from the AURORA study ...
Kefeng Sun, Claudia Jomphe, Nathalie H. Gosselin, Leon Pheng, Chandrasekar Durairaj, Yaming Hang, Indranil Bhattacharya   +6 more
wiley   +1 more source

Severe thrombocytopenia is associated with adverse pregnancy outcomes in patients with obstetric antiphospholipid syndrome. [PDF]

Eur J Med Res
Jin J, Zhang M, Cai X, Hou Y, Xiang X, Hou L, Li J, Li C.   +7 more
europepmc   +1 more source

Neonatal thrombocytopenia

, 1971
Ronald G. Strauss
openalex   +1 more source

Deep Brain Stimulation in a Child with Aicardi‐Goutières Syndrome‐7 (AGS7): A Case Report and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan, Siddharth Seth, Sunita Venkateswaran, Wei Kang Lim, Andrea LeBlanc‐Millar, Sara Breitbart, Vivek Pai, Asif Doja, Alfonso Fasano, George M. Ibrahim, Carolina Gorodetsky   +10 more
wiley   +1 more source

Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Parth Patwari, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Z. X. Zhu   +8 more
wiley   +1 more source