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Immune Thrombocytopenia [PDF]

Hematology, 2010
Immune thrombocytopenia (ITP) comprises a heterogeneous group of disorders characterized by autoimmune-mediated platelet destruction and impairment of thrombopoiesis. ITP may occur in the absence of an evident predisposing etiology (primary ITP) or secondary to a growing list of associated conditions (secondary ITP), and must be differentiated from ...
Adam, Cuker, Douglas B, Cines
openaire   +2 more sources

Panitumumab-Associated Drug-Induced Immune Thrombocytopenia in a Patient with Colorectal Cancer

Case Reports in Oncology, 2021
Severe thrombocytopenia is a rare adverse event of panitumumab. Here, we report the first patient with metastatic colorectal cancer who developed severe thrombocytopenia, diagnosed as panitumumab-associated drug-induced immune thrombocytopenia (DITP).
Shigemasa Takamizawa, Hirokazu Shoji, Hidekazu Hirano, Koji Izutsu, Shun Yamamoto, Satoru Iwasa, Yoshitaka Honma, Natsuko Okita, Atsuo Takashima, Ken Kato, Narikazu Boku   +10 more
doaj   +1 more source

Thrombocytopenia as a Bleeding Risk Factor in Atrial Fibrillation and Coronary Artery Disease: Insights From the AFIRE Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary ...
Raisuke Iijima, Masahide Tokue, Masato Nakamura, Satoshi Yasuda, Koichi Kaikita, Masaharu Akao, Junya Ako, Tetsuya Matoba, Katsumi Miyauchi, Nobuhisa Hagiwara, Kazuo Kimura, Atsushi Hirayama, Kunihiko Matsui, Hisao Ogawa   +13 more
doaj   +1 more source

Thrombocytopenia-related outcome and pattern in preterm neonates hospitalized in neonatology unit: A single-center experience

Iraqi Journal of Hematology
BACKGROUNDS: In preterm newborns, thrombocytopenia is one of the most often observed hematologic findings. Most cases of thrombocytopenia are mild to moderate, self-limiting, and have a short duration; nevertheless, in rare cases, it can result in ...
Sambhav Jain, Bablu Kumar Gaur, Manish Sharma, Rupa Rajbhandari Singh   +3 more
doaj   +1 more source

Immune Thrombocytopenia: A Rare Presentation of Pulmonary Sarcoidosis

European Journal of Case Reports in Internal Medicine, 2021
Thrombocytopenia may be the initial presentation of sarcoidosis, which is a systemic granulomatous disorder. Various pathophysiological mechanisms have been identified. Immune thrombocytopenia often has a severe presentation but may respond favourably to
Mariana da Silva Leal, Carolina Amado, Bárbara Paracana, Flávio Pereira, Mariana Sousa, Aurora Mendes   +5 more
doaj   +1 more source

Bleeding in neonates with severe thrombocytopenia: a retrospective cohort study

BMC Pediatrics, 2022
Background Severe neonatal thrombocytopenia is a rare disease with multiple etiologies. Severe thrombocytopenia with bleeding is life-threatening and has attracted significant attention from clinicians.
Ting Peng, Yuanyuan Shan, Peng Zhang, Guoqiang Cheng   +3 more
doaj   +1 more source

Vancomycin Induced Thrombocytopenia – Protracted Course in a Hemodialysis Patient

Case Reports in Oncology, 2019
Vancomycin induced thrombocytopenia (VIT) is an uncommon side effect of vancomycin which can manifest from mild petechiae to life-threatening bleed.
Nisha Elizabeth Ajit, Sindhu Priya Devarashetty, Samip Master   +2 more
doaj   +1 more source

Prevalence and aetiology of moderate and severe thrombocytopenia in a tertiary and quaternary centre in KwaZulu-Natal

African Journal of Laboratory Medicine, 2020
Background: Thrombocytopenia is a common haematological disorder, characterised by platelet counts below 150 × 109/L. The aetiology of thrombocytopenia is multifactorial; notably, in a misdiagnosis this condition may be due to pre-analytical laboratory ...
Ayanda G. Jali, Bongani B. Nkambule
doaj   +1 more source

Whole-genome sequence of Macaca fascicularis: liver tissue

BMC Genomic Data, 2023
Objectives Thrombocytopenia is a condition that causes a low amount of blood platelets. Platelets are blood cells that play an essential role in blood coagulation.
Eun-Hye Seo, Jeong-Hwan Kim, Da-Hee Kim, Jung-Hwa Oh, Seon-Young Kim   +4 more
doaj   +1 more source

Bevacizumab-induced immune thrombocytopenia in an ovarian cancer patient with mixed connective tissue disease: case report and literature review

Frontiers in Immunology
Drug-induced immune thrombocytopenia is an adverse reaction marked by accelerated destruction of blood platelets. In cancer therapy, thrombocytopenia has many other causes including bone marrow suppression induced by chemotherapeutic agents, infection ...
Yunting Zhang, Fanchun Yang, Jining Wang, Hui Fu, Fuming Shen, Jie Liu, Dongjie Li   +6 more
doaj   +1 more source