Results 61 to 70 of about 432,090 (383)

Thrombocytopenia as a Bleeding Risk Factor in Atrial Fibrillation and Coronary Artery Disease: Insights From the AFIRE Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary ...
Raisuke Iijima, Masahide Tokue, Masato Nakamura, Satoshi Yasuda, Koichi Kaikita, Masaharu Akao, Junya Ako, Tetsuya Matoba, Katsumi Miyauchi, Nobuhisa Hagiwara, Kazuo Kimura, Atsushi Hirayama, Kunihiko Matsui, Hisao Ogawa   +13 more
doaj   +1 more source

Thrombocytopenia and increased risk of adverse outcome in COVID-19 patients [PDF]

PeerJ, 2022
Background Thrombocytopenia was common in the coronavirus disease 2019 (COVID-19) patients during the infection, while the role of thrombocytopenia in COVID-19 pathogenesis and its relationship with systemic host response remained obscure.
Yang Yuan, Gang Wang, Xi Chen, Xiao-Lei Ye, Xiao-Kun Li, Rui Li, Wan-Li Jiang, Hao-Long Zeng, Juan Du, Xiao-Ai Zhang, Hao Li, Li-Qun Fang, Qing-Bin Lu, Wei Liu   +13 more
doaj   +2 more sources

Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]

, 2016
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine, Espasandin, Yesica Romina, García, Alejandro Jorge, Glembotsky, Ana Claudia, Goette, Nora Paula, Grodzielski, Matías, Heller, Paula Graciela, Lev, Paola Roxana, Marta, Rosana Fernanda, Molinas, Felisa Concepción, Pierdominici, Marta S., Riveros, Dardo Alberto   +11 more
core   +1 more source

Endemic Severe Fever with Thrombocytopenia Syndrome, Vietnam

Emerging Infectious Diseases, 2019
Severe fever with thrombocytopenia syndrome (SFTS), a tickborne viral disease, has been identified in China, South Korea, and Japan since 2009. We found retrospective evidence of SFTS virus (SFTSV) infection in Vietnam, which suggests that SFTSV ...
Xuan Chuong Tran, Yeojun Yun, Le Van An, So‐Hee Kim, N. Thao, Phan Kim C. Man, J. Yoo, S. Heo, Nam-Hyuk Cho, Keun-Hwa Lee   +9 more
semanticscholar   +1 more source

Platelet‐activating immune complexes identified in critically ill COVID‐19 patients suspected of heparin‐induced thrombocytopenia

Journal of Thrombosis and Haemostasis, 2021
Thrombocytopenia and thrombosis are prominent in coronavirus disease 2019 (COVID‐19), particularly among critically ill patients; however, the mechanism is unclear.
Izhac Nazy, Stefan D. Jevtic, J. Moore, Angela Huynh, James W. Smith, J. Kelton, D. Arnold   +6 more
semanticscholar   +1 more source

Use of second-line and beyond maintenance therapies in adult patients with primary immune thrombocytopenia in Europe: a parallel study of six prospective multicenter national registries

Haematologica
Not available.
Guillaume Moulis, Frederick Chen, Giuseppe Carli, Waleed Ghanima, Karolin Trautmann-Grill, Thomas Stauch, Alexandra Schifferli, Haroon Miah, Manuela Rueter, Lisanna Ghiotto, Riccardo Tomasello, Annabell Georgi, Vickie McDonald, Francesco Zaja, Heidi Hassel Pettersen, Thomas Kühne, Maria Luisa Lozano, Tomás José González-López, Drew Provan, Marc Michel, Nichola Cooper, Francesco Rodeghiero   +21 more
doaj   +1 more source

Expanded CURB-65: A new score system predicts severity of community-acquired pneumonia with superior efficiency [PDF]

, 2016
Aim of this study was to develop a new simpler and more effective severity score for communityacquired pneumonia (CAP) patients. A total of 1640 consecutive hospitalized CAP patients in Second Affiliated Hospital of Zhejiang University were included ...
Dong, Xiao Jun, Falcone, Marco, Farcomeni, Alessio, Liu, Jin Liang, Lu, Rui Qing, Luo, Shu Ya, Shi, Ling Xian, Venditti, Mario, Wu, Xue Jie, Xu, Feng, Zhao, Ying Li, Zhou, Hui   +11 more
core   +1 more source

A Retrospective Observational Single-Centre Study on the Burden of Immune Thrombocytopenia (ITP) [PDF]

, 2012
Background: German data on economic consequences of immune thrombocytopenia (ITP) are limited. Patients and Methods: A retrospective, observational study based on chart review of adult patients with a confirmed diagnosis of ITP was conducted at a German ...
Ackermann, Birgit, Bauer, Matthäus, Baumann, Anja, Berger, Karin, Ostermann, Helmut, Schopohl, Dorothee, Shlaen, Rita   +6 more
core   +1 more source

A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors. [PDF]

, 2015
BackgroundThis first-in-human study evaluated AMG 208, a small-molecule MET inhibitor, in patients with advanced solid tumors.MethodsThree to nine patients were enrolled into one of seven AMG 208 dose cohorts (25, 50, 100, 150, 200, 300, and 400 mg ...
Amore, Benny, Beaupre, Darrin M, Caudillo, Isaac, Deng, Hongjie, Fu, Siqing, Hong, David S, Hwang, Yuying C, Janku, Filip, Khan, Rabia, Kurzrock, Razelle, Lee, Peter, Loberg, Robert, Lockhart, A Craig, Ngarmchamnanrith, Gataree, Rosen, Peter   +14 more
core   +9 more sources

Prognostic value of thrombocytopenia during hospitalizations in intracerebral hemorrhage patients

Frontiers in Neurology
BackgroundThe thrombocytopenia influences prognoses of critically ill patients. There are few studies exploring the prognostic value of thrombocytopenia among ICH patients.
Hao Feng, Xiaoquan Luo, Anhui Fu, Ruoran Wang, Fei Qiao   +4 more
doaj   +1 more source