Results 161 to 168 of about 78,032 (168)

Diagnostic accuracy of the PLASMIC score in patients with suspected thrombotic thrombocytopenic purpura: A systematic review and meta‐analysis

Transfusion, 2020
The PLASMIC score was developed to identify patients with thrombotic microangiopathy who are most likely to have immune thrombotic thrombocytopenic purpura (TTP) and benefit from therapeutic plasma exchange (TPE).
Koosha Paydary, Emma Banwell, Jiayi Tong, Yong Chen, A. Cuker   +4 more
semanticscholar   +1 more source

First‐in‐patient study of hetrombopag in patients with chronic idiopathic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2020
Idiopathic thrombocytopenic purpura (ITP) especially refractory and (or) relapsed ITP, is a serious and global health burden and its clinical treatment is far from being satisfied.
Zhenlei Wang, Li Chen, Fengkui Zhang, Hua Lu, Xiequn Chen, Aidong Wen, Jianmin Luo, Yu Hu, Yongsheng Wang, T. Niu, Li Zheng   +10 more
semanticscholar   +1 more source

An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura

Expert Review of Hematology, 2019
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, consumption thrombocytopenia, and organ injury. TTP pathophysiology is based on a severe
B. Joly, P. Coppo, A. Veyradier
semanticscholar   +1 more source

Pembrolizumab-induced thrombotic thrombocytopenic purpura

Journal of Oncology Pharmacy Practice, 2019
Introduction Pembrolizumab is a humanised monoclonal antibody targeting the receptor programmed cell death protein-1 (PD-1), with anti-tumour activity demonstrated for many malignancies.
M. Dickey, A. Raina, P. Gilbar, Brendan Wisniowski, Joel T Collins, Bhaskar Karki, A. Nguyen   +6 more
semanticscholar   +1 more source

The role of N-acetylcysteine in the treatment of thrombotic thrombocytopenic purpura

Journal of Thrombosis and Thrombolysis, 2016
A. Rottenstreich, S. Hochberg-Klein, D. Rund, Y. Kalish   +3 more
semanticscholar   +1 more source

Twice‐daily therapeutical plasma exchange‐based salvage therapy in severe autoimmune thrombotic thrombocytopenic purpura: the French TMA Reference Center experience

European Journal of Haematology, 2016
M. Soucemarianadin, Y. Benhamou, Yahsou Delmas, C. Pichereau, É. Maury, F. Pène, J. Halimi, C. Presne, J. Thouret, A. Veyradier, P. Coppo   +10 more
semanticscholar   +1 more source

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

Nature, 2001
G. Levy, W. Nichols, E. Lian, T. Foroud, J. McClintick, B. McGee, A. Yang, D. Siemieniak, K. R. Stark, R. Gruppo, R. Sarode, S. Shurin, V. Chandrasekaran, S. Stabler, H. Sabio, E. Bouhassira, J. Upshaw, D. Ginsburg, H. Tsai   +18 more
semanticscholar   +1 more source