Results 61 to 70 of about 93,360 (257)

Thrombotic thrombocytopenic purpura

open access: yesMedicina Universitaria, 2015
AbstractThrombotic thrombocytopenic purpura (TTP) is a disease with a high rate of mortality if a proper treatment is not instated. Plasmapheresis with plasmatic exchange is the treatment of choice. Diagnosis is performed demonstrating microangiopathic hemolytic anemia, a negative direct Coombs test and thrombocytopenia.
Tellez Hinojosa, Carlos Alberto   +2 more
openaire   +3 more sources

Evaluating the appropriateness of fresh frozen plasma transfusions in two tertiary teaching hospitals

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Despite efforts to standardise practice using evidence‐based guidelines, fresh frozen plasma (FFP) remains the blood component most frequently prescribed inappropriately. This study assessed the appropriateness of FFP transfusion in two tertiary teaching hospitals and analysed the characteristics of appropriate and inappropriate ...
Jongmin Kim   +3 more
wiley   +1 more source

Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2017
Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis.
Prabath K. Abeysundara   +5 more
doaj  

Caplacizumab reduces the frequency of major thromboembolic events, exacerbations and death in patients with acquired thrombotic thrombocytopenic purpura

open access: yesJournal of Thrombosis and Haemostasis, 2017
Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi   +8 more
semanticscholar   +1 more source

Rituximab reduces risk for relapse in patients with thrombotic thrombocytopenic purpura.

open access: yesBlood, 2016
Publisher's Note: There is an [Inside Blood Commentary][1] on this article in this issue. To the editor: Recent systematic reviews assessing the role of rituximab in the management of patients with acquired thrombotic thrombocytopenic purpura (TTP)[1 ...
E. E. Page   +4 more
semanticscholar   +1 more source

Idiopathic thrombocytopenic purpura

open access: yesJapanese Journal of Thrombosis and Hemostasis, 2008
Point(1)診断は血小板減少をきたす他の疾患の除外を基本とする.(2)血小板数と出血症状の程度,背景因子やライフスタイルに基づいて治療適応を決める.(3)治療はまずステロイド療法,次いで摘脾を行う.(4)ITPと診断されればまずH. pyloriを検索し,陽性であれば除菌療法を優先する.
openaire   +3 more sources

Endothelial Glycocalyx: The Missing Link Between Angiogenic Imbalance in Preeclampsia and Systemic Inflammation in HELLP Syndrome

open access: yesComprehensive Physiology, Volume 15, Issue 4, August 2025.
Endothelial glycocalyx may be the missing link between angiogenic factors, inflammatory regulation, and endothelial maternal dysfunction in early‐onset preeclampsia and HELLP syndrome. ABSTRACT The pathophysiology of preeclampsia and HELLP syndrome relies on systemic vascular endothelial dysfunction, resulting from angiogenic imbalance due to abnormal ...
Anthony Atallah   +4 more
wiley   +1 more source

Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection

open access: yesCase Reports in Surgery, 2014
First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical
Wil L. Santivasi   +2 more
doaj   +1 more source

Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever

open access: yesCase Reports in Oncology, 2017
Primary immune thrombocytopenia (ITP) – also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura – is an acquired thrombocytopenia caused by autoantibodies against platelet antigens.
Cherisse Baldeo   +2 more
doaj   +1 more source

Open or closed? Understanding the molecular mechanisms and clinical implications of ADAMTS13's conformation

open access: yesHemaSphere, Volume 9, Issue 7, July 2025.
Abstract By proteolyzing prothrombotic von Willebrand factor (VWF) multimers, ADAMTS13 (A Disintegrin And Metalloproteinase with ThromboSpondin type‐1 repeats, member 13) ensures balanced hemostasis and prevents microvascular thrombosis. ADAMTS13's conformational regulation is not only crucial for its enzymatic function, but also for the ...
Quintijn Bonnez, Karen Vanhoorelbeke
wiley   +1 more source

Home - About - Disclaimer - Privacy