Results 61 to 70 of about 93,360 (257)
Thrombotic thrombocytopenic purpura
AbstractThrombotic thrombocytopenic purpura (TTP) is a disease with a high rate of mortality if a proper treatment is not instated. Plasmapheresis with plasmatic exchange is the treatment of choice. Diagnosis is performed demonstrating microangiopathic hemolytic anemia, a negative direct Coombs test and thrombocytopenia.
Tellez Hinojosa, Carlos Alberto+2 more
openaire +3 more sources
Abstract Background Despite efforts to standardise practice using evidence‐based guidelines, fresh frozen plasma (FFP) remains the blood component most frequently prescribed inappropriately. This study assessed the appropriateness of FFP transfusion in two tertiary teaching hospitals and analysed the characteristics of appropriate and inappropriate ...
Jongmin Kim+3 more
wiley +1 more source
Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture
Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis.
Prabath K. Abeysundara+5 more
doaj
Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi+8 more
semanticscholar +1 more source
Rituximab reduces risk for relapse in patients with thrombotic thrombocytopenic purpura.
Publisher's Note: There is an [Inside Blood Commentary][1] on this article in this issue. To the editor: Recent systematic reviews assessing the role of rituximab in the management of patients with acquired thrombotic thrombocytopenic purpura (TTP)[1 ...
E. E. Page+4 more
semanticscholar +1 more source
Idiopathic thrombocytopenic purpura
Point(1)診断は血小板減少をきたす他の疾患の除外を基本とする.(2)血小板数と出血症状の程度,背景因子やライフスタイルに基づいて治療適応を決める.(3)治療はまずステロイド療法,次いで摘脾を行う.(4)ITPと診断されればまずH. pyloriを検索し,陽性であれば除菌療法を優先する.
openaire +3 more sources
Endothelial glycocalyx may be the missing link between angiogenic factors, inflammatory regulation, and endothelial maternal dysfunction in early‐onset preeclampsia and HELLP syndrome. ABSTRACT The pathophysiology of preeclampsia and HELLP syndrome relies on systemic vascular endothelial dysfunction, resulting from angiogenic imbalance due to abnormal ...
Anthony Atallah+4 more
wiley +1 more source
Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection
First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical
Wil L. Santivasi+2 more
doaj +1 more source
Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever
Primary immune thrombocytopenia (ITP) – also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura – is an acquired thrombocytopenia caused by autoantibodies against platelet antigens.
Cherisse Baldeo+2 more
doaj +1 more source
Abstract By proteolyzing prothrombotic von Willebrand factor (VWF) multimers, ADAMTS13 (A Disintegrin And Metalloproteinase with ThromboSpondin type‐1 repeats, member 13) ensures balanced hemostasis and prevents microvascular thrombosis. ADAMTS13's conformational regulation is not only crucial for its enzymatic function, but also for the ...
Quintijn Bonnez, Karen Vanhoorelbeke
wiley +1 more source