Results 71 to 80 of about 93,052 (258)

A prospective non‐inferiority trial of pathogen reduced platelets compared to non‐pathogen reduced platelets for correction of viscoelastic platelet function testing in cardiac surgery

Transfusion, Volume 65, Issue 7, Page 1293-1306, July 2025.
Abstract Background Cardiac surgery on cardiopulmonary bypass (CPB) may alter platelet (PLT) function causing bleeding. The goal of this study is to evaluate the hemostatic effect of PRT‐PLTs compared to untreated PLTs stored in platelet additive solution (PAS) following transfusion in bleeding patients undergoing cardiac surgery on CPB.
Magali J. Fontaine, Jackline J. M. Lasola, Aidaelis Martinez‐Hernandez, Juliana N. Marshall, Soren Bentzen, Min Zhan, Parvez M. Lokhandwala, Kenichi Tanaka, Carlos H. Villa, Alexis Jones, Chintamani D. Atreya, Reney A. Henderson   +11 more
wiley   +1 more source

Rituximab reduces risk for relapse in patients with thrombotic thrombocytopenic purpura.

Blood, 2016
Publisher's Note: There is an [Inside Blood Commentary][1] on this article in this issue. To the editor: Recent systematic reviews assessing the role of rituximab in the management of patients with acquired thrombotic thrombocytopenic purpura (TTP)[1 ...
E. E. Page, J. K. Kremer Hovinga, Deirdra R. Terrell, S. Vesely, J. George   +4 more
semanticscholar   +1 more source

Vitamin B12 deficiency-induced pseudothrombotic microangiopathy without macrocytosis presenting with acute renal failure: a case report

Journal of Medical Case Reports, 2018
Background Vitamin B12 deficiency-induced thrombotic microangiopathy, known as pseudothrombotic microangiopathy, is a rare condition which resembles the clinical features of thrombotic thrombocytopenic purpura but requires a markedly different treatment.
Jennifer Vanoli, Andrea Carrer, Roberto Martorana, Guido Grassi, Michele Bombelli   +4 more
doaj   +1 more source

Immunosuppressive and Non‐Immunosuppressive Drugs for Heart Xenotransplantation in Humans: Is Europe Ready?

Xenotransplantation, Volume 32, Issue 4, July/August 2025.
ABSTRACT Xenotransplantation is becoming an emerging field of interest for the treatment of end‐stage heart disease. In fact, the shortage of human heart donors in European countries requires the increasing investigation of alternative strategies such as heart xenotransplantation.
Nicola Pradegan, Annamaria Tolomeo, Diego Ciccarelli, Emanuele Cozzi, Antonio Vitiello, Andrea Zovi, Gino Gerosa   +6 more
wiley   +1 more source

Graves disease-induced thrombotic thrombocytopenic purpura: a case report

Journal of Medical Case Reports, 2019
Background Thrombotic thrombocytopenic purpura is an autoimmune disease that carries a high mortality. Very few case reports in the literature have described a relationship between Graves disease and thrombotic thrombocytopenic purpura. We present a case
Saira Chaughtai, Ijaz Khan, Varsha Gupta, Zeeshan Chaughtai, Raquel Ong, Arif Asif, Mohammad A. Hossain   +6 more
doaj   +1 more source

Rational Design of Single‐Domain Antibodies Targeting the Central Nervous System Neurite Outgrowth Inhibitor Nogo‐A

Applied Research, Volume 4, Issue 3, June 2025.
The development of a nanobody for Nogo‐A, a potent neurite outgrowth inhibitor crucial in multiple sclerosis, is reported using a rational design approach. The nanobody targets the Nogo‐A ectodomain at the S1PR2 receptor‐binding region with submicromolar KD.
Vaidehi Roy Chowdhury, Alexander Röntgen, Matthew Greenig, Yanira Méndez Gómez, Sebastian P. Spiegel, Magdalena Nowinska, Aubin Ramon, Pietro Sormanni, Andrew Chan, Michele Vendruscolo   +9 more
wiley   +1 more source

Wiskott–Aldrich syndrome that was initially diagnosed as immune thrombocytopenic purpura secondary to a cytomegalovirus infection

SAGE Open Medical Case Reports, 2018
Wiskott–Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott–Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital
Ryota Kaneko, Shohei Yamamoto, Naoko Okamoto, Kosuke Akiyama, Ryosuke Matsuno, Daisuke Toyama, Akihiro Hoshino, Kohsuke Imai, Keiichi Isoyama   +8 more
doaj   +1 more source

A Red Skin in the Setting of Chickenpox: A Rare Report of Eosin Toxicity

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Eosin Yellowish (Eosin‐Y) is an effective treatment option for a range of dermatological conditions. It is crucial to carefully identify patients presenting systemic adverse reactions related to topical aqueous Eosin‐Y overuse and to monitor them closely during short‐term use to prevent severe complications.
Bahareh Abtahi‐Naeini, Fereshte Rastegarnasab, Zahra Pourmoghaddas, Shadi Asad Samani, Saeed Yousefian, Zahra‐Sadat Mirian   +5 more
wiley   +1 more source

Clinical importance of ADAMTS13 activity during remission in patients with acquired thrombotic thrombocytopenic purpura.

Blood, 2016
To the editor: Acute episodes of acquired autoimmune thrombotic thrombocytopenic purpura (TTP) are associated with severe ADAMTS13 deficiency, commonly defined as
E. E. Page, J. K. Kremer Hovinga, Deirdra R. Terrell, S. Vesely, J. George   +4 more
semanticscholar   +1 more source

Long-term Kidney Outcomes in Patients With Acquired Thrombotic Thrombocytopenic Purpura

Kidney International Reports, 2017
Severe acute kidney injury (AKI) and chronic kidney disease (CKD) are considered to be uncommon in patients with acquired thrombotic thrombocytopenic purpura.
Dustin J. Little, Lauren M. Mathias, Evaren E. Page, Johanna A. Kremer Hovinga, Sara K. Vesely, James N. George   +5 more
doaj   +1 more source