IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Background From 20 to 50% of patients who survive an acute episode of the acquired form of thrombotic thrombocytopenic purpura relapse but clinical and laboratory markers of recurrence are not well established.Design and Methods In 109 patients enrolled ...
Flora Peyvandi +15 more
doaj +1 more source
Púrpura trombopénica inmune : múltiples tratamientos para una enfermedad [PDF]
En el present treball es descriuen les principals característiques clíniques de la purpura trombopènica immune, com ara, la distribució per sexes, edat, la presència d'hemorràgies en el moment del diagnòstic i la seva gravetat, la xifra de plaquetes i la
Lluch García, Rafael +3 more
core
Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Bõze, Tamás +9 more
core +1 more source
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås +4 more
wiley +1 more source
NEONATAL THROMBOCYTOPENIC PURPURA: REPORT OF TWO CASES AND REVIEW OF LITERATURE [PDF]
Introduction: Severe neonatal thrombocytopenia is a hematological emergency that can be due to increased platelet destruction (such as immune-mediated and peripheral platelet consumption) or congenital failure of platelet production.
Abiodun MT, Badejoko B, Oluwafemi RO
doaj
Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M +23 more
core +1 more source
Differentiating between severe hypertension and thrombocytopenic purpura as the cause of thrombotic microangiopathy in a patient with Castleman disease: a case report and literature review [PDF]
Itamar Feldman +3 more
openalex +1 more source
European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations related to cancer‐causing infections, namely H. pylori, HPV, HBV, HCV and HIV, positioned as recommendation number 12.
Catharina Johanna Alberts +18 more
wiley +1 more source
Influences of various hormones on the megakaryocyte in bone-marrow tissue culture [PDF]
In our study on the influences of various hormones and various endocrines on the megakaryocyte function by means of bone-marrow tissue culture, we obtained the following. 1.
Hiraki, Kiyoshi +2 more
core +1 more source

