Results 51 to 60 of about 145,313 (292)

Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort [PDF]

, 2021
Mark M. G. Mulder, LIoyd Brandts, Renée A. G. Brüggemann, Marcel Koelmann, Alexander S. Streng, Renske H. Olie, Hester A. Gietema, Henri M.H. Spronk, Iwan C.C. van der Horst, Jan-Willem E. M. Sels, Joachim E. Wildberger, Sander M. J. van Kuijk, Ronny M. Schnabel, Hugo Ten Cate, Yvonne Henskens, Bas C. T. van Bussel   +15 more
openalex   +1 more source

A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya, Venkata Yellepeddi, Ann Marie B. Prazak, Mathangi Gopalakrishnan   +3 more
wiley   +1 more source

Menopausal hormone therapy and heart disease prevention: desired or valid?

Кардиоваскулярная терапия и профилактика, 2019
Cardiovascular diseases are the main cause of death for women in older age groups. For many decades, specialists have tried to prevent their development by the use of estrogen.
V. I. Podzolkov, A. E. Bragina, N. M. Podzolkovа   +2 more
doaj   +1 more source

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Clinical Outcomes in Non Valvular Atrial Fibrillation Patients Receiving Oral Anticoagulation Therapy using CHA2DS2-VASc and HAS-BLED Scores: A Cohort Study from Western Gujarat, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Non Valvular Atrial Fibrillation (NVAF) is one of the most common sustained arrhythmias. The Congestive heart failure, Hypertension, Age, Diabetes, Stroke/TIA (or Thrombembolism), Vascular disease, Age, Sex category (for CHA2DS2-VASc) score,
Sohilkhan Riyazkhan Pathan, Bharat M Gajjar, Sunilkumar Karna, Kushal Pujara   +3 more
doaj   +1 more source

Simultaneous Repair of Iatrogenic Left Atrial and Aortic Perforations Using Ductus Arteriosus Occluders: A Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Iatrogenic perforation of the left atrium and aorta during transseptal puncture (TSP) is a rare but potentially life‐threatening complication. This report presents the case of an elderly male patient with a 20‐year history of atrial fibrillation who experienced this complication during a scheduled left atrial appendage closure procedure ...
Zhihao Wu, Shumin Ouyang, Minqi Liao, Lihua Chen, Haixian Yin, Jianping Zhou, Suxia Guo   +6 more
wiley   +1 more source

Usage and safety of direct oral anticoagulants at patients with atrial fibrillation and planned diagnostic procedures, interventions, and surgery

Heart and Mind, 2019
Atrial fibrillation (AF) affects about 2% of the population, with the increasing prevalence with age. It is associated with poorer quality of life, effort intolerance, frequent hospitalizations, heart failure, and increased risk of systemic embolization,
Marko Mornar Jelavic, Goran Krstacic, Hrvoje Pintaric   +2 more
doaj   +1 more source

Myocardial infarction, prothrombotic genotypes, and venous thrombosis risk: The Tromsø Study

Research and Practice in Thrombosis and Haemostasis, 2020
Background The risk of venous thromboembolism (VTE) is increased after a myocardial infarction (MI). Some prothrombotic genotypes associated with VTE have also been associated with risk of MI.
Joakim K. Sejrup, Vania M. Morelli, Maja‐Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen, Tom Wilsgaard, John‐Bjarne Hansen, Sigrid K. Brækkan   +7 more
doaj   +1 more source

Utility of D-dimers and intermediate-dose prophylaxis for venous thromboembolism in critically ill patients with COVID-19 [PDF]

, 2020
Maxime G. Zermatten, Olivier Pantet, Francisco J. Gómez, Antoine Schneider, Marie Méan, Lucia Mazzolai, Olivier Hügli, Pierre‐Alexandre Bart, Matthaios Papadimitriou‐Olivgeris, Lorenzo Alberio   +9 more
openalex   +1 more source

Real‐World Edoxaban Concentrations in Older Patients Receiving Reduced‐Dose Regimens

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world edoxaban concentrations in older patients receiving reduced‐dose regimens. Low trough concentrations (< 12 ng/mL) were associated with an increased risk of thromboembolism. Among patients meeting the ELDERCARE‐AF criteria, low drug levels were more frequent with the 15 mg regimen than with the 30 mg regimen.
Sung‐Chun Tang, Shin‐Yi Lin, Chih‐Hao Chen, Yen‐Bin Liu, Li‐Ting Ho, Ching‐Hua Kuo, Yu‐Fong Peng, Chih‐Fen Huang, Jiann‐Shing Jeng   +8 more
wiley   +1 more source