Results 41 to 50 of about 209,409 (314)

Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]

open access: yes, 2014
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
A. John Camm   +72 more
core   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli   +10 more
wiley   +1 more source

Simple measures can improve care in our hospitals : an audit of venous thromboembolism practice [PDF]

open access: yes, 2013
: Venous thromboembolism (VTE) is a serious but preventable complication of hospitalisation. Doctors still sometimes fail to adhere to them, thus putting patients at risk and incurring considerable expense for the national health service.
Azzopardi, Stephanie   +3 more
core  

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Freqüência da profilaxia mecânica para trombose venosa profunda em pacientes internados em uma unidade de emergência de Maceió Frequency of mechanical prophylaxis for deep venous thrombosis in patients admitted to an emergency room in Maceió, Brazil

open access: yesJornal Vascular Brasileiro, 2008
CONTEXTO: A trombose venosa profunda (TVP) é uma doença de ocorrência multidisciplinar e freqüente, incluindo as complicações relacionadas a ela, como o tromboembolismo pulmonar (TEP).
Nathalia Leilane Berto Machado   +2 more
doaj   +1 more source

Hormone replacement therapy [PDF]

open access: yes, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Inherited thrombophilia: Diagnostic approach

open access: yesIraqi Journal of Hematology, 2017
Hemostatic abnormalities include both bleeding and thrombosis disorders. Adherence to most common guidelines for the diagnosis of thrombophilia is recommended especially in some developing countries.
Rahem Mahdy Rahem   +1 more
doaj   +1 more source

Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period [PDF]

open access: yes, 2010
Some women are at risk of forming blood clots in a deep vein during pregnancy, after a caesarean birth, or during the first few weeks after childbirth. If part of the clot breaks off and lodges in a blood vessel in the lungs, it can be life-threatening ...
Abou-Nassar   +92 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

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