Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) [PDF]
<p>Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle ...
Frölich Marijke +59 more
core +1 more source
Venous thromboembolism in orthopedic surgery: Global guidelines [PDF]
Venous thromboembolism (VTE) is a severe complication that can occur after major orthopedic procedures. As VTE-related morbidity and mortality are a significant concern for both medical professionals and patients, and preventative measures are typically ...
Javad Parvizi +5 more
core +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Venous thromboembolism and pregnancy [PDF]
Maristella D’Uva1, Pierpaolo Di Micco2, Ida Strina1, Giuseppe De Placido1Department of Obstetrics and Gynecology and Human Reproduction, “Federico II” University of Naples, Naples, Italy; 2Internal Medicine Division ...
Maristella D’Uva +3 more
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Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen +11 more
wiley +1 more source
Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim +11 more
wiley +1 more source
Coagulation and thrombotic risk in thalassemia intermedia
As the life expectancy of β-thalassemia patients has markedly improved over the last few decades, several manifestations are increasingly recognized.
A.T. Taher, K.M. Musallam
doaj +1 more source
Swedish obstetric thromboprophylaxis guideline: background and update
Risk estimation concerning venous thromboembolism (VTE) and thromboprophylaxis for those at risk is routine in pregnancy. For 20 years, Swedish obstetricians have followed a weighted-risk algorithm guideline for risk estimation, based on which patient ...
Pelle G. Lindqvist +2 more
doaj +1 more source
Postoperative In-Stent Thrombus Formation Following Frozen Elephant Trunk Total Arch Repair
ObjectivesOur aim was to investigate the occurrence and clinical consequence of postoperative in-stent thrombus formation following the frozen elephant trunk (FET) procedure.MethodsPostoperative computed tomography angiography (CTA) scans of all 304 ...
Tim Walter +7 more
doaj +1 more source
INCORPORATION OF ALPHA2- PLASMIN INHIBITOR INTO PLASMA CLOTS OF HEALTHY CONTROLS AND PATIENTS WITH VENOUS THROMBOEMBOLISM [PDF]
Alpha2-plasmin inhibitor (A2PI) is the main physiological inhibitor of plasmin. In the final phase of coagulation, activated factor XIII (FXIIIa) cross-links A2PI to fibrin and it has been shown that only cross-linked A2PI can efficiently inhibit ...
Dauda, Marriam Akua Amprofua
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