Results 81 to 90 of about 127,924 (293)

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Nusrat Jahan Moon   +10 more
wiley   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

open access: yesAnnals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian   +9 more
wiley   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

open access: yes, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Al, R.Y.   +9 more
core   +1 more source

A Case of Venous Tissue Dissection During Transcatheter MitraClip Surgery

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The MitraClip system has been widely used to treat mitral regurgitation. The complications associated with MitraClip surgery typically include clip detachment and mitral valve injury. However, cases of venous tissue dissection during surgery are relatively rare.
Shumin Ouyang   +5 more
wiley   +1 more source

A cross sectional study on thrombolysis in ST elevation myocardial infarction and its assessment with respect to ST segment resolution and time delay [PDF]

open access: yesAl Ameen Journal of Medical Sciences
Background: ST elevation myocardial infarction is a leading cause of death in India. Several socio-economic factors lead to delay in seeking thrombolysis. Aims and Objectives: To analyse the effect of time delay on the success of thrombolysis.
P.R. Bijeesh   +3 more
doaj  

Intraocular hemorrhage in patients misdiagnosed with central retinal artery occlusion treated with thrombolysis

open access: yesFrontiers in Neurology
IntroductionThe diagnosis of acute central retinal artery occlusion (CRAO) is commonly delayed in emergency departments (ED) where ophthalmologists are rarely available for immediate consultation.
Daniel V. Adamkiewicz   +14 more
doaj   +1 more source

Angioscopy Visualized a Residual Free‐Floating Thrombus in Mild Carotid Artery Stenosis Following Acute MCA Occlusion: A Case Report

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Carotid free‐floating thrombus (CFFT) is a rare yet severe cause of the ischemic stroke. Early identification and appropriate management are crucial to prevent recurrent embolic events. A 76‐year‐old man experienced sudden left‐sided hemiparesis and dysarthria.
Hirofumi Matsubara   +3 more
wiley   +1 more source

Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With The Guidelines Stroke Registry

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intravenous thrombolysis for acute ischemic stroke (AIS) is a proven effective treatment. Whether thrombolysis in patients with AIS with recent direct oral anticoagulant (DOAC) use is safe and efficacious is not well established.
Shadi Yaghi   +15 more
doaj   +1 more source

Clinical characteristics of unknown symptom onset stroke patients with and without diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch [PDF]

open access: yes, 2017
Background: Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) mismatch was suggested to identify stroke patients with unknown time of symptom onset likely to be within the time window for thrombolysis. Aims: We aimed
Boutitie, Florent   +18 more
core   +2 more sources

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