Results 81 to 90 of about 68,801 (240)

Advances in the treatment of cerebral venous sinus thrombosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Cerebral venous sinus thrombosis (CVST) is a special type of stroke with an increasing rate of diagnosis and a higher rate of disability and mortality. Currently, anticoagulant therapy, systemic venous thrombolysis, arterial thrombolysis, contact venous ...
Hong-guang WANG, Yi-mu FAN
doaj  

Cangrelor Dosing, Administration, and Clinical Outcomes for Patients Undergoing Complex and High‐Risk Percutaneous Coronary Interventions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cangrelor reduces thrombotic events in patients undergoing percutaneous coronary intervention (PCI), with the advantage of rapid onset and offset. However, premature discontinuation may increase the risk of acute thrombosis for patients undergoing complex/high‐risk PCI (CHIP).
Siyu Ma, Wendy Y. Cheng, Yinong Liang, Josephine Bryar, Gwyneth Wei, Joshua D. Niznik, Christina Yin, Sue Liu‐Yi, Jimmy L. Kerrigan   +8 more
wiley   +1 more source

Safety of thrombolysis in acute ischemic stroke patients with previous aortic abdominal aneurysm repair

Journal of Stroke and Cerebrovascular Diseases
Objective: Intravenous thrombolysis is the standard treatment for acute ischemic stroke (AIS), but its safety in patients with a history of abdominal aortic aneurysm (AAA) repair remains unclear.
Walter Duarte-Celada, MD, Katherine Rivas, MD, Pichatorn Suppakitjanusant, MD, Pamela Davila-Siliezar, MD, Myriam Vijil, MD, Ximena Gamboa, MD, Chanaka N. Kahathuduwa, MD, PhD, Riichi Ota, MD, Ross Raedeke, Darko Quispe-Orozco, MD   +9 more
doaj   +1 more source

Physiology‐Guided Drug‐Coated Balloon Angioplasty: What We Know and What is Yet to be Understood

Catheterization and Cardiovascular Interventions, EarlyView.
Marco Frazzetto, Filippo Luca Gurgoglione, Bharat Khialani, Sandeep Basavarajaiah, Bernardo Cortese   +4 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Association Between Triglyceride‐Glucose Index and in‐Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC‐IV Database

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study utilized the Medical Information Mart for Intensive Care database to investigate the association between the triglyceride–glucose (TyG) index and in‐hospital intensive care unit (ICU) readmission in patients with ischemic stroke (IS). Among 2929 patients, 24.0% experienced ICU readmission.
Di Zhang, Ying‐Lun Chen, Jian Zhang, Xiang‐Jun Hu   +3 more
wiley   +1 more source

An Explainable Two-Stage Machine Learning Model for Predicting the Post-Thrombolysis Complications in Stroke Patients: A Multi-Center Study

Research
Current tools for predicting the thrombolysis risk in patients after stroke exhibit limited event prediction in early post-thrombolysis hemorrhagic events. This highlights an unmet medical need to improve the tools for stroke management.
Hongling Zhu, Qing Ye, Shurui Wang, Hongsen Cai, Mairihaba Maimaiti, Jinsheng Lai, Chuan Qin, Ping Zhang, Yanyan Chen, Qiushi Luo, Hong Wu, Danyang Chen, Shiling Chen, Shudan Zhu, Yuting Lv, Yanxiang Xu, Jian Zhang, Benshan Hu, Yuanxiang Yin, Yan Xie, Dongmei Zhu, Xiaoxing Ming, Zhouping Tang, Hesong Zeng   +23 more
doaj   +1 more source