Results 101 to 110 of about 12,086 (222)

Development and characterization of site specific target sensitive liposomes for the delivery of thrombolytic agents [PDF]

, 2011
In recent times, search for potent and highly selective thrombolytic agents with minimal side effects has become a major area of research. The aim of the present study was to develop and characterize target sensitive (TS) liposomes encapsulating ...
Agrawal, G. P., Bhuvaneshwar Vaidya, Manasa K. Nayak, Dash, Debabrata, Vaidya, Bhuvaneshwar, Vyas, Suresh P., G.P. Agrawal, Nayak, Manasa K., Debabrata Dash, Suresh P. Vyas   +9 more
core   +1 more source

Heterogeneity in plasma p‐tau217 response and its association with cognitive trajectories under lecanemab treatment

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Plasma phosphorylated tau 217 (p‐tau217) is a promising biomarker for monitoring treatment response in Alzheimer's disease (AD), but its longitudinal dynamics and clinical relevance remain unclear. METHODS In this prospective real‐world study, 153 patients with early AD receiving lecanemab were analyzed.
Sung Hoon Kang, Yu Jeong Park, Seungyun Lee, Jimin Kang, Seongin Lee, Eun Seong Lee, Hye Na Jung, Inseon Ryoo, Hyundoo Hwang, Kwangho Choi, Jae Seon Eo, Sang‐Il Suh, Kyungmi Oh, Seong‐Beom Koh   +13 more
wiley   +1 more source

Intravenous Thrombolysis Combined With Endovascular Treatment Versus Endovascular Treatment Alone in Acute Ischemic Stroke due to Tandem Lesions: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 8, August 2026.
Our systematic review and meta‐analysis evaluate whether intravenous thrombolysis (IVT) plus endovascular therapy (EVT) outperforms EVT alone in patients with acute ischemic stroke due to tandem lesions. Pooled data from nine studies involving 1756 patients demonstrate that IVT + EVT is associated with significantly higher rates of functional ...
Wenqian Wei, Chongxu Zhong, Jian Tang, Liufei Chen, Kunlong Yao, Liyong Li, Shengliang Shi, Yueling Zhang, Jian Zhang   +8 more
wiley   +1 more source

Catheter‐Based Therapies for Intermediate‐High Risk Pulmonary Embolism: A Protocol for a Systematic Review With Bayesian Pairwise and Network Meta‐Analyses

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Intermediate‐high risk pulmonary embolism (PE) represents a clinically challenging subgroup of acute PE, characterized by right ventricular dysfunction and increased risk of hemodynamic deterioration despite treatment with anticoagulation therapy.
Jacob Hindborg Hovmann, Thomas Skjoldborg Sornn‐Friese, Frederik Færgemann Lau, Niels Brandt, Isak Mazanti Cold, Janus C. Jakobsen, Jasmin Dam Lukoschewitz, Alasdair D. Henderson, Anne Sophie Overgaard Olesen, Jens Dahlgaard Hove, Jesper Kjærgaard, Johannes Grand   +11 more
wiley   +1 more source

STUDIES ON THROMBOLYTIC AND ANTI-HELMINTIC ACTIVITY OF Cocccinea grandis [PDF]

, 2014
Traditional system of medicine consists of large number of plants with various medicinal and pharmacological values and hence represents a priceless tank of new bio active molecules.
Deepti, B; Vignan Pharmacy College, Vadlamudi, Guntur, Andhra Pradesh 522213, India
core   +2 more sources

Evaluation of Membrane-Stabilizing and Clot-Lysing Activities of the Chloroform Fraction of Rhizomes: An Model With Molecular Docking

Natural Product Communications
Objective Cardiovascular diseases (CVDs) remain a primary reason for death, and current thrombolytic agents face significant limitations due to side effects and high costs.
Md. Sabbir Hossain, Sajib Ghosh, Md. Abu Bakar Siddique Jami, Md. Sakib Al Hasan, Joy Sarker, Md. Golam Sadik, A. H. M. Khurshid Alam   +6 more
doaj   +1 more source

Door to Needle Time in Acute Myocardial Infarction Patients

Journal of Rawalpindi Medical College, 2017
To determine the current door-to-needle time for the administration of fibrinolytics for acute myocardial infarction (AMI) in emergency room. Methods: In this cross sectional study patients presenting with acute myocardial infarction (AMI) were included.
Muhammad Usman
doaj  

FIRST REPORT ON FIBRINOLYTIC AND THROMBOLYTIC ACTIVITY OF EUTYPHOEUS GAMMIEI AN EARTHWORM SPECIES COLLECTED FROM TRIPURA, NORTHEAST INDIA [PDF]

, 2018
Objective: The present investigation for the first time evaluated the in vitro fibrinolytic and thrombolytic activities of crude extracts from Eutyphoeus gammiei, native, large size earthworm of Tripura, Northeast, India.
Debnath, Madhusudan, Saha, Susmita, Kumar Sil, Samir   +2 more
core   +1 more source

Streptokinase‐Induced Serum Sickness: A Case Report

Clinical Case Reports
Serum sickness is rare; however, there is a significant hypersensitivity reaction to streptokinase used in different cardiac problems. Treatment often involves discontinuing the offending agent and administering corticosteroids. This case underscores the
Bibek Shrestha, Rebicca Pradhan, Pradeep Shrestha, Sudip Bastakoti   +3 more
doaj   +1 more source

Delayed thrombolytic treatment of older patients with acute myocardial infarction. [PDF]

, 2009
OBJECTIVE: To determine demographic and clinical factors associated with delayed thrombolysis in patients with acute myocardial infarction. DESIGN: A retrospective cohort. SETTING: 37 Minnesota hospitals during the time periods October 1992-July 1993 and
Gao, Xiaoming, Gurwitz, Jerry H., Soumerai, Stephen B., McLaughlin, Thomas J, Willison, Donald J.   +4 more
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