Results 161 to 170 of about 68,289 (278)

Multi‐Layered Genomic and Clinical Analysis Identifies Novel Variants, Co‐Occurring Single Nucleotide Polymorphism Pairs, and Clinical Determinants of Host‐Pathogen Interaction in COVID‐19 Severity

open access: yesJournal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić   +7 more
wiley   +1 more source

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell–Selective Bioactivity

open access: yesMacromolecular Bioscience, Volume 26, Issue 6, June 2026.
Sulfated PHEMA‐based polyelectrolyte brushes are introduced as a reductionist platform to probe glycosaminoglycan‐inspired bioactivity. High charge density governs growth factor interactions and is associated with distinct vascular cell responses, enabling balanced endothelial and smooth muscle cell co‐culture.
Andrea Cosimi   +9 more
wiley   +1 more source

Short‐Term, Cycle‐Synchronized Adjunctive Therapy With Crocus Total Glucosides Tablets for Cardiac Protection Against Cancer Therapy‐Related Cardiac Dysfunction in Breast Cancer Patients: A Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Cycle‐synchronized CTGT therapy attenuates LVGLS decline and reduces CTRCD in breast cancer patients. This randomized, double‐blind, placebo‐controlled trial assessed whether cycle‐synchronized CTGT prevent CTRCD in 120 breast cancer patients receiving chemotherapy.
Xiaoling Liu   +11 more
wiley   +1 more source

A Case Report of Shwachman‐Diamond Syndrome Caused by Heterozygous Variants in the EFL1 Gene and Literature Review

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
We report a neonatal SDS patient with earliest onset of symptoms. The c.2935C>T and c.3149_3151delCAC compound heterozygous variants reported in this study expand the mutational spectrum of this disease. ABSTRACT Objective This investigation reports on a Shwachman‐Diamond syndrome (SDS) case arising from compound heterozygous genetic variations ...
Xiaoying Zhou   +4 more
wiley   +1 more source

Prediction of massive intraoperative blood transfusion requirement in lung transplantation. [PDF]

open access: yesFront Med (Lausanne)
Tao X   +10 more
europepmc   +1 more source

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

open access: yesOrgan Medicine, Volume 3, Issue 2, Page 119-124, June 2026.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai   +8 more
wiley   +1 more source

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