Results 51 to 60 of about 68,289 (278)

Impact of thromboplastin reagents on monitoring INR in a patient with triple-positive antiphospholipid syndrome: a case report

Frontiers in Immunology
IntroductionAntiphospholipid syndrome (APS) is an autoimmune disease characterized by a hypercoagulable state and recurrent thromboembolism (TE). Patients with triple-positive antiphospholipid antibodies (APAs) are at the highest risk of TE.
Lóránt Varju, Lóránt Varju, Zsuzsa Bagoly, Zsuzsa Bagoly, Éva Ajzner, Rita Orbán-Kálmándi, Rita Orbán-Kálmándi, Anna Zsófia Kádár, Anna Zsófia Kádár, Judit Nevelős, Péter Ilonczai   +10 more
doaj   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Anticoagulant properties of rabbit lungs in tissue thromboplastin-induced intravascular coagulation

, 1997
This study was conducted in order to examine possible anticoagulant properties of the lungs during tissue thromboplastin-induced intravascular coagulation.
Jespersen, Jørgen; id_orcid, Gram, Jørgen, Albrechtsen, Ole K., Tvedskov, Tove F., Hansen, Knud B., Vad, Henrik, Jespersen, Jørgen   +6 more
core   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

British Journal of Clinical Pharmacology, EarlyView.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi, Angela L. Chiew, Keith Harris, Geoffrey K. Isbister   +3 more
wiley   +1 more source

Co-relation of coagulation profile with glycemic index in patients with type 2 diabetes

Journal of Family Medicine and Primary Care
Background: Diabetes mellitus (DM) has emerged as a significant global concern that accounts for nearly 90% of type 2 DM cases worldwide and characterized by insulin resistance. Hyperglycemia in diabetes leads to increased fibrinogen levels and activates
Sushil Kumar, Soma Dey, Abhilasha Bankul, Bandana Kumari, Bankim Das, Goutham Giri   +5 more
doaj   +1 more source

Acquired factor VIII inhibitor syndrome: A rare cause of hematuria

Indian Journal of Urology, 2015
A 50-year-old woman presented with gross hematuria for 1 month. Clinical examinations, laboratory investigations, ultrasound and contrast computed tomography were normal, except anemia. Cystoscopy revealed bloody efflux from the right side.
Muthuvel Seral Kannan, Thallur Ramakrishnan Raj Kumar, Srinivasan Subramanian   +2 more
doaj   +1 more source

Thromboplastin: Nomenclature and Preparation of Protein-Free Material Different From Platelet Factor 3 or Lipid Activator

, 1958
A method was developed for obtaining a highly active fraction from rabbit brain tissue which meets all of the requirements of a complete thromboplastin in the ‘traditional’ sense. The material we have isolated is called brain thromboplastin.
Walter H. Seegers, Eugen R. Hecht, Min H. Cho   +2 more
core   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

A Study of Haematological and Haemostasis Parameters and Hypercoagulable State in Tuberculosis Patients in Northern India and the Outcome with Anti-Tubercular Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Tuberculosis is one of the leading infectious diseases with high morbidity and mortality in the developing countries. Tuberculosis is also rarely associated with hypercoagulable state and very limited literature is available on this ...
ADITYA SINGH KUTIYAL, NARESH GUPTA, SANDEEP GARG, HARMANJIT SINGH HIRA   +3 more
doaj   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source