Results 171 to 180 of about 7,460 (217)
Transcriptome profiling of megakaryocytes and platelets: Application to <i>GP9</i>- and <i>IKZF5</i>-related thrombocytopenia. [PDF]
HemasphereDe Wispelaere K +7 more
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Hematopoietic Niche Hijacking in Bone Metastases: Roles of Megakaryocytes, Erythroid Lineage Cells, and Perivascular Stromal Subsets. [PDF]
BiomedicinesAlkhatib AR +3 more
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Letter regarding "Plasma concentration of thrombopoietin in dogs with immune thrombocytopenia". [PDF]
J Vet Intern MedWun MK.
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Seminars in Hematology, 2015
The production of platelets is a complex process that involves hematopoietic stem cells (HSCs), their differentiated progeny, the marrow microenvironment and hematopoietic cytokines. Much has been learned in the 110 years since James Homer Wright postulated that marrow megakaryocytes were responsible for blood platelet production, at a time when ...
exaly +3 more sources
The production of platelets is a complex process that involves hematopoietic stem cells (HSCs), their differentiated progeny, the marrow microenvironment and hematopoietic cytokines. Much has been learned in the 110 years since James Homer Wright postulated that marrow megakaryocytes were responsible for blood platelet production, at a time when ...
exaly +3 more sources
Role of thrombopoiesis in leishmaniasis
Cytokine, 2021The blood vascular system of mammals is unique in nature; inhabited with a pool of tiny small cell fragments called platelets; attributed with the most important patrolling tasks to check integrity of the entire endothelial landscape. Their production is tightly coupled with hematopoietic system where everything starts from self renewable multipotent ...
Arkajyoti Mukherjee +3 more
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Proceedings, annual meeting, Electron Microscopy Society of America, 1990
In effective thrombopoies is has been inferred to occur in several disease sates from considerations of megakaryocyte mass and platelet kinetics. Microscopic examination has demonstrated increased numbers of megakaryocytes, with a typical forms particularly pronounced, in primary myelofibrosis.
JM Radley, SL Ellis
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In effective thrombopoies is has been inferred to occur in several disease sates from considerations of megakaryocyte mass and platelet kinetics. Microscopic examination has demonstrated increased numbers of megakaryocytes, with a typical forms particularly pronounced, in primary myelofibrosis.
JM Radley, SL Ellis
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Pathologic thrombopoiesis of rheumatoid arthritis
Rheumatology International, 2003Rheumatoid arthritis (RA) is frequently complicated by thrombocytosis correlated with disease activity. The exact pathogenetic mechanism(s) that cause increased platelet counts in RA are still unknown. Recent investigations indicate that proinflammatory pleiotropic cytokines of RA also have megakaryocytopoietic/thrombopoietic properties.
Ihsan, Ertenli +5 more
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The Journal of Pediatrics, 1965
An extract of fresh normal human plasma was shown to contain a factor capable of inducing platelet formation in rats. This thrombopoietic factor, which is labile on storage, was markedly deficient in the plasma of a child with chronic congenital thrombocytopenic purpura who responded repeatedly to infusions of normal human plasma.
Irving Schulman +4 more
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An extract of fresh normal human plasma was shown to contain a factor capable of inducing platelet formation in rats. This thrombopoietic factor, which is labile on storage, was markedly deficient in the plasma of a child with chronic congenital thrombocytopenic purpura who responded repeatedly to infusions of normal human plasma.
Irving Schulman +4 more
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Thrombopoiesis: Capturing the unicorn
Current Biology, 1994The elusive factor that stimulates megakaryocytes to produce platelets has at last been found; as well as its physiological interest, this factor--thrombopoietin--may be of considerable therapeutic importance.
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Romiplostim: A novel thrombopoiesis-stimulating agent
American Journal of Health-System Pharmacy, 2009The pharmacology, pharmacokinetics, dosage and administration, efficacy, safety, effects on quality of life, and place in therapy of romiplostim are reviewed.Romiplostim is a second- generation thrombopoietic agent that stimulates the thrombopoietin receptor and platelet production without inducing production of autoantibodies. Romiplostim, a peptibody,
Sarah, Perreault, Julianna, Burzynski
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