Results 191 to 200 of about 7,460 (217)
Some of the next articles are maybe not open access.
Mechanisms of embryonic thrombopoiesis
2021Platelets are generated by specialized cells called megakaryocytes (MKs) throughout embryonic development and adulthood. In adult bone marrow, MKs form and release proplatelets into circulation which mature into functional peripheral platelets. However, platelet generation in embryos is not fully understood. This is due to limitations of existing mouse
openaire +1 more source
Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 2004
Although platelets were already discovered light-microscopically in the 19th century, it became only clear in 1906 that they originate from megakaryocytes. The discovery of thrombopoietin in 1994 facilitated research on the origin of platelets, because this growth factor enabled expansion of megakaryocytes in culture.
openaire +1 more source
Although platelets were already discovered light-microscopically in the 19th century, it became only clear in 1906 that they originate from megakaryocytes. The discovery of thrombopoietin in 1994 facilitated research on the origin of platelets, because this growth factor enabled expansion of megakaryocytes in culture.
openaire +1 more source
[Current models of thrombopoiesis].
Der Pathologe, 2011Platelets are essential corpuscular blood components required for hemostasis. They are released from precursor cells in the bone marrow by cellular fragmentation into the blood stream. Although some aspects of platelet biogenesis are well known, studying its occurrence in vivo has been mostly unsatisfactory.
openaire +1 more source
Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis
Nature Communications, 2022Mina N F Morcos +2 more
exaly
Humoral control of thrombopoiesis.
Blood cells, 1981There is increasing evidence that an important mechanism by which platelet production is regulated depends upon a humoral substance (thrombopoietin) that affects the production of platelets by megakaryocytes. Plasma from thrombocytopenic donors increases the rate of appearance or concentrations of subsequently administered Na235SO4 or selenomethionine ...
J, Levin, B L, Evatt
openaire +1 more source