Results 61 to 70 of about 3,260 (169)

Risk of thrombosis and bleeding following CAR T‐cell therapy: Insights from the Dutch “Follow that CAR!” registry

HemaSphere, Volume 10, Issue 7, July 2026.
Abstract Chimeric antigen receptor (CAR) T‐cell therapy has significantly improved outcomes in patients with relapsed/refractory aggressive large B‐cell lymphoma (R/R LBCL). Although thrombosis and bleeding complications have been increasingly reported, their clinical relevance and risk factors remain unclear, also due to heterogeneity between ...
Amica K. Ko, Pim G. N. J. Mutsaers, Lukas M. van Kleij, Amária Vledder, Elise R. A. Pennings, Anne M. Spanjaart, Janneke W. de Boer, Kylie Keijzer, Astrid M. P. Demandt, Jaap A. van Doesum, Suzanne van Dorp, Margot Jak, Maria T. Kuipers, Tom van Meerten, Marjolein W. M. van der Poel, Joost S. P. Vermaat, Frank W. G. Leebeek, Marie J. Kersten, Mandy N. Lauw   +18 more
wiley   +1 more source

Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two cases and review of the literature

Frontiers in Cardiovascular Medicine
IntroductionPrimary immune thrombocytopenia is an autoimmune bleeding disorder characterized by variable immune-mediated platelet destruction. These patients have reported thrombotic complications, both venous and arterial, in addition to bleeding ...
Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu   +16 more
doaj   +1 more source

Efficacy and safety of high doses of eltrombopag for treating adult immune thrombocytopenia: Results from a multicentre retrospective cohort study

British Journal of Haematology, EarlyView.
Salomé Dahan, Stéphanie Guillet, Olivier Fain, Delphine Gobert, Stéphane Cheze, Florent Broca, Bertrand Godeau, Marc Michel   +7 more
wiley   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu, Zining Wang, Jiaming Hu, Chunyan Liu, Rong Fu   +4 more
wiley   +1 more source

Pharmacist intervention through protocol-based pharmacotherapy management is effective to ensure safety in invasive procedures for chronic liver disease

Journal of Pharmaceutical Health Care and Sciences
Background The risk of hemorrhagic complications in patients with chronic liver disease during invasive procedures should be considered. Patients with low platelet counts were administered platelet products prior to procedures based on a physician's ...
Yuuka Shibata, Yuki Koga, Yuki Sato, Emiko Mashida, Tomokazu Kawaoka, Eisuke Murakami, Kei Amioka, Yusuke Johira, Kensuke Naruto, Takanori Taogoshi, Tomoharu Yokooji, Masataka Tsuge, Hiroaki Matsuo   +12 more
doaj   +1 more source

The role of eltrombopag in the management of hepatitis C virus-related thrombocytopenia

Hepatic Medicine: Evidence and Research, 2013
Fazal-i-Akbar Danish,1 Saeeda Yasmin21James Paget University Hospital, Great Yarmouth, Norfolk, United Kingdom; 2Shifa International Hospital, Islamabad, PakistanAbstract: Eltrombopag is a 2nd generation thrombopoietin-receptor agonist. It binds with the
Danish FA, Yasmin S
doaj  

Renal transplant in a patient with idiopathic thrombocytopenic purpura refractory to steroid and intravenous immunoglobulin

Indian Journal of Transplantation, 2019
Chronic kidney disease in immune thrombocytopenia (ITP) is uncommon, and renal transplant in this setting is especially rare. We present a case of successful renal transplantation in a patient with chronic ITP refractory to steroid and intravenous ...
Shubham Agarwal, Pankaj Beniwal, Dhananjai Agarwal, Vinay Rathore   +3 more
doaj   +1 more source

Case Report: A case of pediatric persistent refractory ITP responsive to avatrombopag

Frontiers in Immunology
Immune thrombocytopenia (ITP) is a rare hematologic disorder characterized by low platelet counts due to an immune-mediated destruction of platelets. While corticosteroids, intravenous immunoglobulin (IVIG) are the mainstays of treatment, a subset of ...
Antonella Sau, Gianfranco Di Prinzio, Daniela Onofrillo, Anna Caterina Russo, Nicole Santoro, Mauro Di Ianni   +5 more
doaj   +1 more source

A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia

Shanghai Jiaotong Daxue xuebao. Yixue ban
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 ...
LIU Jiayu, HUANG Fang, HAO Siguo
doaj   +1 more source