Key Features of Contemporary Pilot and Feasibility Trials: Protocol for a Methodological Study
ABSTRACT Background Randomised clinical trials (RCTs) are costly undertakings requiring careful design, planning and conduct. Failure to achieve timely participant recruitment, separation between intervention groups and adequate follow‐up contributes to waste in research.
Aske Tøgern +7 more
wiley +1 more source
Venous thromboembolism risk following surgery during the COVID‐19 pandemic
Summary Introduction SARS‐CoV‐2 infection is associated with an increased risk of venous thromboembolism. Data are lacking on how this risk altered during the COVID‐19 pandemic and following vaccination. We aimed to evaluate the 90‐day risk of postoperative venous thromboembolism during the pandemic. Methods We performed a retrospective cohort study of
Andrew Jackson +7 more
wiley +1 more source
Background The optimal duration for thromboprophylaxis after colorectal cancer surgery remains uncertain. We sought to compare the effectiveness and safety of long-term thromboprophylaxis to that of short-term thromboprophylaxis in preventing venous ...
Ying Zhang +5 more
doaj +1 more source
Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]
© Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A +8 more
core +2 more sources
Abstract Background Therapeutic plasma exchange (TPE) using exclusively albumin replacement fluid depletes coagulation factors, particularly fibrinogen, and concerns about performing multiple consecutive daily procedures due to iatrogenic bleeding exist. Fibrinogen testing to guide bleeding risk stratification is vague.
Jay S. Raval +7 more
wiley +1 more source
An update on prevention of venous thromboembolism in hospitalized acutely ill medical patients
Both the recently updated consensus guidelines published by the American College of Chest Physicians, and the International Union of Angiology recommend thromboprophylaxis with either low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) in
Kleber Franz-Xaver, Samama Meyer
doaj +1 more source
Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England [PDF]
For women with preeclampsia, BMI >30 kg/m2, infection, or those having cesarean delivery, VTE risk remained elevated for 6 weeks postpartum.For women with postpartum hemorrhage or preterm birth, the relative rate of VTE was only increased for the ...
Abdul Sultan +42 more
core +1 more source
IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics [PDF]
Background Heparin-induced thrombocytopenia (HIT) is a thromboembolic complication that can occur with unfractionated heparin (UFH) or low molecular weight heparin (LMWH).
Satoru Motokawa +8 more
core +1 more source
Establishment of prophylactic enoxaparin dosing recommendations to achieve targeted anti-factor Xa concentrations in children with CHD [PDF]
Background Enoxaparin may be used to prevent central venous catheter-related thrombosis in patients with CHD. We aimed to determine whether current enoxaparin dosing regimens effectively achieve anti-factor Xa concentrations within prophylactic goal ...
Israel, Emily N. +2 more
core +1 more source
Venous Thromboprophylaxis in Spine Surgery
Study Design: Review article. Objective: A review of the literature on postoperative initiation of thrombophylactic agents following spine surgery.
Anthony M. Alvarado MD +4 more
doaj +1 more source

