Results 101 to 110 of about 1,025,996 (357)

Extravascular coagulation regulates haemostasis independently of activated platelet surfaces in an in vivo mouse model

Communications Biology
While the conventional understanding of haemostatic plug formation is that coagulation proceeds efficiently on the surface of activated platelets at the vascular injury site to form a robust haemostatic plug, this understanding does not explain the ...
Asuka Sakata, Kohei Tatsumi, Naoki Matsumoto, Nigel Mackman, Suguru Harada, Ryohei Kawasaki, Yukiko Okuyama-Nishida, Tetsuhiro Soeda, Keiji Nogami, Midori Shima   +9 more
doaj   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Dabigatran Plasma Measurement to Guide the Management of Acute Bleeding and Thrombotic Complications

European Journal of Case Reports in Internal Medicine, 2018
Oral anticoagulant therapy is recommended for the prevention and treatment of venous thromboembolism and to prevent stroke in non-valvular atrial fibrillation.
Maurizio Tala, Oriana Paoletti, Claudia Dellanoce, Rossella Morandini, Carlo Valtulina, Maria Sessa, Sophie Testa   +6 more
doaj   +1 more source

Clinical and laboratory practice for lupus anticoagulant testing : an International Society of Thrombosis and Haemostasis Scientific and Standardization Committee survey [PDF]

, 2019
Background Current guidelines have contributed to more uniformity in the performance and interpretation of lupus anticoagulant (LA) testing. However, points to reconsider include testing for LA in patients on anticoagulation, cut-off values, and ...
Cohen, Hannah, Devreese, Katrien, Mackie, Ian J., the International Society for Thrombosis and Haemostasis Scientific and Standardization Committee for Lupus Anticoagulant/Antiphospholipid Antibodies, [missing]   +3 more
core   +2 more sources

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period [PDF]

, 2010
Some women are at risk of forming blood clots in a deep vein during pregnancy, after a caesarean birth, or during the first few weeks after childbirth. If part of the clot breaks off and lodges in a blood vessel in the lungs, it can be life-threatening ...
Abou-Nassar, Abou-Nassar, Alfirevic, Alikhan, Andersen, Atrash, Badawy, Barbour, Bates, Blomback, Brenner, Brenner, Brenner, Brenner, Brenner, Brenner, Brill-Edwards, Brocklehurst, Brocklehurst, Brocklehurst, Burrows, Casele, Casele, Chistolini, Cohen, Conard, Connolly, Cornette, Dargaud, Dendrinos, Dittmer, Ellison, Ellison, Ellison, Empson, Farquharson, Friederich, Gates, Gates, Gates, Gherman, Gibson, Hall, Hamersley, Harenberg, Heilman, Heilmann, Heit, Hill, Hill, Howell, Högberg, Kaandorp, Kakkos, Kamin, Knight, Krauss, Kutteh, Kutteh, Larciprete, Letsky, Lewis, Lindhagen, Lindqvist, Macklon, Middeldorp, Nelson-Piercy, Noble, Orme, Paull, Pettila, Pettila, Pomp, Rai, Ramos, Rey, Rey, Rodger, Rodger, Rodger, Rutherford, Segal, Simpson, Stefano, Stephenson, Taylor, Testroote, Thaler, Tulppala, Veciana, Walker, Welti, Wu   +92 more
core   +1 more source

Nitric Oxide‐Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant

Advanced Materials Interfaces, EarlyView.
We report a metal‐free, nitric oxide (NO)‐generating coating in which poly(allylamine hydrochloride) (PAH) is covalently immobilized onto titanium. The coating catalyzes NO generation from the endogenous S‐nitrosothiol GSNO, retains activity after multiple reuse cycles and pH exposures, and maintains endothelial cell viability while modulating ...
Siti Nur Asyura Adzlan, Kang Lin, Shu Geng, Qingqing Fan, Franco Centurion, Zifei Han, Federico Mazur, Rona Chandrawati   +7 more
wiley   +1 more source

Analysis of the potential of cancer cell lines to release tissue factor-containing microvesicles: correlation with tissue factor and PAR2 expression [PDF]

, 2016
BackgroundDespite the association of cancer-derived circulating tissue factor (TF)-containing microvesicles and hypercoagulable state, correlations with the incidence of thrombosis remain unclear.MethodsIn this study the upregulation of TF release upon ...
A Bharthuar, A Delluc, A Falanga, A Rank, A Rank, AA Khorana, AA Khorana, Anthony Maraveyas, AS Wolberg, BA Lwaleed, C Ettelaie, C Ettelaie, C Hernández, C Sapet, Camille Ettelaie, E Camerer, E Campello, E Cocco, ES Breimo, F Doormaal van, F Langer, GW Tormoen, H Kothari, I Pabinger, J Ahamed, J Thaler, J Thaler, J Thaler, JA Bastarache, JE Geddings, JH Morrissey, John Greenman, K Haubold, KG Livak, L Hu, LV Rao, M Davila, Mary EW Collier, ME Collier, ME Collier, ME Collier, ME Collier, ME Tesselaar, ML Rand, N Satta, N Tavoosi, Naima E. Benelhaj, NS Key, P Bucciarelli, R Flaumenhaft, RI Kushak, S Butenas, SJ Compton, SK Dasgupta, Sophie Featherby, T Kawamoto, V Combes, W Ruf   +57 more
core   +2 more sources

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Journal of Experimental Medicine, 2012
Deep vein thrombosis initiation is mediated by cross talk between monocytes, neutrophils, and platelets.
Marie-Luise von Brühl, K. Stark, Alexander Steinhart, S. Chandraratne, Ildiko Konrad, M. Lorenz, A. Khandoga, A. Tirniceriu, R. Coletti, Maria Koellnberger, Robert A. Byrne, I. Laitinen, A. Walch, A. Brill, S. Pfeiler, D. Manukyan, S. Braun, Philipp Lange, J. Riegger, J. Ware, Annekathrin Eckart, Selgai Haidari, M. Rudelius, C. Schulz, Katrin Echtler, V. Brinkmann, M. Schwaiger, K. Preissner, D. Wagner, N. Mackman, B. Engelmann, S. Massberg   +31 more
semanticscholar   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source