Results 51 to 60 of about 1,059,322 (407)
Summary1. Obesity is a major risk factor for cardiovascular disease. An increased body mass index (BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent thrombosis after percutaneous interventions. Studies in mouse models of obesity and induced arterial or venous thrombosis have provided insights into the mechanisms ...
Schaefer, Katrin+1 more
openaire +4 more sources
SARS-CoV-2 Infection-Associated Aortic Thrombosis Treated with Oral Factor Xa Inhibition
Coronavirus disease 2019 (COVID-19) is an acute complex systemic disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).While SARS-CoV-2 is known to cause significant pulmonary disease, various extrapulmonary manifestations ...
Alena Strýčková+9 more
doaj +1 more source
Non-Newtonian Effects of Blood Flow on Hemodynamics in Pulmonary Stenosis: Numerical Simulation
This paper aims to explore the construction of an individualized pulmonary artery stenosis model based on computed tomography (CT) images. The stenosis model is simulated using a porous medium, and the numerical simulation is carried out by computational
Fan He, Xinyu Wang, Lu Hua, Tingting Guo
doaj +1 more source
Cerebral Venous Thrombosis Associated with COVID-19
The authors report a unique series of young patients with COVID-19 presenting with cerebral venous system thrombosis. Three patients younger than 41 years of age with confirmed Severe Acute Respiratory Syndrome coronavirus 2 infection had neurologic ...
D. Cavalcanti+11 more
semanticscholar +1 more source
Cancer Therapy–Associated Thrombosis
Patients with cancer have an increased risk of both arterial and venous thrombotic events compared with the general population. Both the site and stage of cancer are known to contribute to the increased risk of thrombotic events.
S. Grover+4 more
semanticscholar +1 more source
Risk marker associations with venous thrombotic events: a cross-sectional analysis. [PDF]
ObjectiveTo examine the interrelations among, and risk marker associations for, superficial and deep venous events-superficial venous thrombosis (SVT), deep venous thrombosis (DVT) and pulmonary embolism (PE).DesignCross-sectional analysis.SettingSan ...
Chan, Virginia T+4 more
core +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez+5 more
wiley +1 more source
Patients with a second venous thromboembolism generally receive anticoagulant treatment indefinitely, although it is known that the recurrence risk diminishes over time while the risk of hemorrhage persists with continued anticoagulation and increases ...
Tom van der Hulle+7 more
doaj +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul+3 more
wiley +1 more source
Intense investigation continues on the pathobiology of stent thrombosis (ST) because of its morbidity and mortality. Because little advance has been made in outcomes following ST, ongoing research is focused on further understanding predictive factors as well as ST frequency and timing in various patient subsets, depending upon whether a drug-eluting ...
Holmes, DR+8 more
openaire +3 more sources