Results 71 to 80 of about 1,025,996 (357)

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets

Nature Communications, 2018
Diabetes is associated with an increased thrombotic response, but the mechanism is unknown. Here the authors demonstrate that compressive force activates integrin αIIbβ3 on discoid diabetic platelets and that platelet aggregates can be eliminated by PI 3-
Lining Ju, James D. McFadyen, Saheb Al-Daher, Imala Alwis, Yunfeng Chen, Lotte L. Tønnesen, Sophie Maiocchi, Brianna Coulter, Anna C. Calkin, Eric I. Felner, Neale Cohen, Yuping Yuan, Simone M. Schoenwaelder, Mark E. Cooper, Cheng Zhu, Shaun P. Jackson   +15 more
doaj   +1 more source

Using the Caprini Risk Score to Increase Awareness of Venous Thrombus Embolism in the Community: Know Your Score II

Clinical and Applied Thrombosis/Hemostasis, 2023
To assess individual participants’ baseline thrombosis risk calculated by Caprini Risk Score (CRS) before injury, illness, or hospitalization occur, to increase the awareness of venous thromboembolism (VTE) by viewing 2 short videos.
Chunping Huang DNP (C), MSN, RN, Joseph Tariman PhD, MBA, ANP-BC, FAAN, Shannon Simonovich PhD, RN, Arav Bongirwar HS, Divya Honavar HS, Mala Niverthi HS, Rashi Modey HS, Joseph Caprini MD, MS, FACS, RVT, DFSVS, Emeritus, Atul Laddu MD, PhD   +8 more
doaj   +1 more source

Thrombosis in COVID‐19

American journal of hematology/oncology, 2020
Thrombotic complications are frequent in COVID‐19 and contribute significantly to mortality and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be upregulated in COVID‐19.
T. Hanff, Amir M. Mohareb, Jay Giri, Jordana B. Cohen, J. Chirinos   +4 more
semanticscholar   +1 more source

Real‐world Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objectives Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), yet the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to: 1) identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel MPH, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Cerebral Venous Thrombosis Associated with COVID-19

American Journal of Neuroradiology, 2020
The authors report a unique series of young patients with COVID-19 presenting with cerebral venous system thrombosis. Three patients younger than 41 years of age with confirmed Severe Acute Respiratory Syndrome coronavirus 2 infection had neurologic ...
D. Cavalcanti, E. Raz, M. Shapiro, S. Dehkharghani, S. Yaghi, K. Lillemoe, E. Nossek, J. Torres, Rajan Jain, H. Riina, A. Radmanesh, P. Nelson   +11 more
semanticscholar   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

Scientific Reports, 2017
Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved.
Klytaimnistra Kiouptsi, Stepan Gambaryan, Elena Walter, Ulrich Walter, Kerstin Jurk, Christoph Reinhardt   +5 more
doaj   +1 more source

Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis [PDF]

, 2005
Background Ultrasound (US) has largely replaced contrast venography as the definitive diagnostic test for deep vein thrombosis (DVT). We aimed to derive a definitive estimate of the diagnostic accuracy of US for clinically suspected DVT and identify ...
A Cogo, A Cogo, A Elias, A Elias, A Gongolo, A Markel, A Miselli, AF Aburahma, AG Aitken, AJ Comerota, AJ Comerota, AJ Sutton, Alex Sutton, AT Irvine, AW Lensing, B Kassai, B van Ramshorst, B Wolf, BD Lewis, BG Birdwell, BG Birdwell, BN Raghavendra, BS Hwang, C Kearon, C Savy-Stortz, D Becker, D Cavaye, D Gaitini, DA Kristo, DC Mitchell, DH O'Leary, DL Rollins, DP Flanigan, DR Anderson, E Bernardi, E Kalodiki, Edwin van Beek, EK Yucel, F Dany, F Pasquariello, FC Sampson, Fiona Sampson, FJ Song, G Guazzaloca, GJ Zhang, GM Baxter, GM Baxter, GP Shields, GP Size, GR Simons, GV Belcaro, H Bounameaux, H Heijboer, H Heijboer, H Rosier, HJ Aronen, HO Leven, I Baumgartner, J De Laveaucoupet, J Howe, J Yao, J Zamora, JC De Valois, JE George, JE George, JF Chance, JG Lijmer, JJ Cranley, JJ Cronan, JJ Deeks, JM Schindler, JP Carpenter, JP Fletcher, JP Laissy, JPJ Archie, JS Ginsberg, K Forbes, K Ouriel, K Walsh, LA Killewich, LW Tick, M Atri, M Dauzat, M Grobety, M Hay, M Mantoni, M Monreal, M Sluzewski, MA Amin, MA Mattos, MCG Holmes, ME McCandless, MJ Bradley, MK Eskandari, MK Zhou, N Labropoulos, N Miller, NH Rosner, OM Pedersen, P De Faucal, P Vogel, PJ Bendick, PL Robertson, PL Robertson, PR Biondetti, PS Wells, PS Wells, PS Wells, PS Wells, PS Wells, PT Appelman, PT Kennedy, R Lindqvist, R Mani, R Poti, R Puls, R Quintavalla, RA Bucek, RA Kraaijenhagen, RB Patterson, SC Rose, SG Thompson, SJ Theodorou, SM Bates, SM Schellong, SM Stevens, Steve Goodacre, Steve Thomas, SW Heim, TE Gudmundsen, TL Turnbull, W Habscheid, W Wysokinski, WD Foley   +133 more
core   +5 more sources

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source