Results 51 to 60 of about 523,717 (316)

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Superficial vein thrombosis and deep vein thrombosis – a comparison

, 2017
Although superficial vein thrombosis is commonly considered a rather minor condition, a number of studies indicate that its consequences can be much more severe.
Krasiński, Zbigniew, Zbigniew Krasiński, Beata Krasińska, Krzysztof Aniukiewicz, Aniukiewicz, Krzysztof, Krasińska, Aleksandra, Krasińska, Beata, Gabriel, Marcin, Aleksandra Krasińska, Marcin Gabriel   +9 more
core   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

Advanced Healthcare Materials, EarlyView.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores, Eva Mueller, Robert Bui, James C. Fredenburgh, Ruiqi Yin, Rawaa Hussain, Rida A. Malik, Thomas Kalab, Dabeer Abdul‐Azeez, Fei Xu, Michael Brook, Jeffrey I. Weitz, Todd Hoare   +12 more
wiley   +1 more source

Effect of bone marrow blood versus peripheral blood on the hemostatic balance of osteoblasts and endothelial cells

Scientific Reports
Bone and bone-marrow (BM) have the same blood supply and thus may be considered as one organ. We previously demonstrated that the microcirculation hemostatic balance that includes heparanase, tissue factor (TF), TF pathway inhibitor (TFPI) and TFPI-2 are
Keren Asayag, Eli Peled, Yonatan Crispel, Chen Yanovich, Haim Cohen, Anat Keren-Politansky, Yona Nadir   +6 more
doaj   +1 more source

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants [version 1; referees: 2 approved]

F1000Research, 2017
The direct oral anticoagulants (DOACs) have now supplanted vitamin K antagonists (VKAs) for the treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit ...
Jeffrey I. Weitz, Iqbal H. Jaffer, James C. Fredenburgh   +2 more
doaj   +1 more source

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Importance of Inhibitor Surveillance During Emicizumab Prophylaxis in Young Children With Hemophilia: An Illustrative Case Series

Case Reports in Hematology
Hemophilia is an X-linked inherited bleeding disorder associated with bleeding, which starts in infancy. The age of initiation of prophylaxis with clotting factor concentrate is limited by the intravenous mode of administration. Emicizumab, a Factor VIII
Kelly A. Bush, Marc Durocher, Jacqueline Limjoco, Courtney D. Thornburg   +3 more
doaj   +1 more source

Material Selection and Geometric Design for Few‐filament Shape Memory Polymer Yarns for Force Generation

Advanced Materials Technologies, EarlyView.
A custom shape memory polymer material selection process relates quantitative application criteria (e.g., compression garment yarns) to material characterization information. The selected materials are manufactured into yarn geometries, which expand the design space by creating structural stress‐strain profiles beyond the nominal material stress‐strain
Michaela Andrews, Susan Mantell, Julianna Abel   +2 more
wiley   +1 more source

A Pressure Microsensor Made of Parylene‐C for Use as Medical Implant

Advanced Materials Technologies, EarlyView.
A monolithic parylene‐C pressure sensor with gold strain gauges provides 6.2 μV$\mu{\rm V}$·mmHg$\cdot{\rm mmHg}$−1$^{-1}$ sensitivity. The morphology of a sputtered thin film strain sensor is granular/columnar, which results in a high gauge factor of 7.5. Thermal bonding and parylene‐C coating create a hermetic cavity.
Ann‐Kathrin Klein, Victor Krajka, Andreas Dietzel   +2 more
wiley   +1 more source