Results 131 to 140 of about 11,766 (177)
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Thrombotic Thrombocytopenic Purpura
Acta Medica Scandinavica, 1952Abstract 1.1. The clinical and pathologic observations of two cases of thrombotic thrombocytopenic purpura are presented. 2.2. This condition is characterized by the clinical triad of (1) hemolytic anemia; (2) thrombocytopenic purpura and (3) mental and neurologic abnormalities which may be bizarre or transient.
F, RACKOW, L, STEINGOLD, J H F, WOOD
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Thrombotic thrombocytopenic purpura
Disease-a-Month, 2014Moschowitz first described thrombotic thrombocytopenic purpura (TTP) in 1925 in a 16-yearold female who presented with fever, petechiae, and a microangiopathic hemolytic anemia. Autopsy examination at the time revealed hyaline thrombi in the vascular beds of many organs. By 1947, several more cases were described and Singer suggested the term TTP.
Albara, Said +3 more
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Thrombotic Thrombocytopenic Purpura
JAMA: The Journal of the American Medical Association, 1991CASE PRESENTATION —Charles T. Bingham III, MD A 27-YEAR-OLD man was transferred to The Johns Hopkins Hospital for evaluation of delirium. Five days prior to admission he had presented to another hospital with hematemesis and syncope. Esophagogastroduodenoscopy revealed the presence of a 0.5-cm gastric ulcer.
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THROMBOTIC THROMBOCYTOPENIC PURPURA
Annals of Internal Medicine, 1953Excerpt Thrombotic thrombocytopenic purpura is a rare disease of which only a few cases have been diagnosed ante mortem.4Because of the rarity of diagnosis, other than at the autopsy table, few lab...
W S, GREEN, T W, GREEN
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Thrombotic Thrombocytopenic Purpura
Thrombosis and Haemostasis, 1995Recent studies indicate that CRTTP patients have excessive shear stress-induced platelet aggregation that is associated with the presence of ULvWF multimers in their plasma and increased vWF-binding to their platelets by flow cytometry. In these CRTTP patients, relapses, excessive shear-aggregation and the presence in their plasma of ULvWF forms are ...
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Thrombotic thrombocytopenic purpura in pregnancy
BJOG: An International Journal of Obstetrics & Gynaecology, 1982Summary. A 20 week primigravida with intrauterine fetal death and the rare occurrence of thrombotic thrombocytopenic purpura (TTP) in pregnancy is presented. Aprotinin has been used to overcome uterine inertia non‐responsive to oxytocin stimulation. TTP was successfully treated with repeated plasmaphereses.
M, Atlas +4 more
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Autoimmunity in Thrombotic Thrombocytopenic Purpura
Seminars in Thrombosis and Hemostasis, 2005In the last few years, an autoimmune hypothesis for the pathogenesis of thrombotic thrombocytopenic purpura (TTP) has been proposed often, with variable success because of inconsistent supporting data. We are now aware that at least one subgroup of TTP patients does present with pathogenic autoantibodies (i.e, anti-ADAMTS13); this group consequently is
Porta C. +2 more
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Thrombotic thrombocytopenic purpura in childhood
Pediatric Blood & Cancer, 2009AbstractThrombotic thrombocytopenic purpura (TTP) is a rare disease, especially in childhood, and has a high mortality rate in the absence of appropriate treatment. It is characterised by microangiopathic haemolytic anaemia and consumptive thrombocytopenia.
Maria C, Bouw +3 more
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Thrombotic Thrombocytopenic Purpura
Annual Review of Medicine, 1988Platelet thrombus formation in small vessels is triggered by certain stimuli, including vascular injury, primary platelet agglutination, or both. The formation and dissolution of platelet thrombi is modulated by proteolysis, plasma factors, PGI2 synthesis and stability, and immune mechanisms.
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Thrombotic Thrombocytopenic Purpura
Annals of Internal Medicine, 1980Excerpt Originally described in 1925 (1), thrombotic thrombocytopenic purpura remained until recently a fulminating and rapidly fatal disorder. Fortunately, it has been rare.
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