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Adult patients with immune thrombocytopenic purpura. New expectations [PDF]

, 2014
Gómez Almaguer, David
core  

Thrombotic Thrombocytopenic Purpura and Evans Syndrome: Validating and Exploring 20 Years of Routine Hospital Care. [PDF]

J Blood Med
Lawrie DA, Hansen DL, Kristensen TL, Carlsen SBIS, Hannig LH, Pedersen PT, Kristensen HB, Lorenzen MOB, Stentoft J, Van Kooten Niekerk PB, Jørgensen MP, Severinsen MT, Dorff MH, Pedersen RS, Glenthøj A, Frederiksen H.   +15 more
europepmc   +1 more source

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Thrombotic thrombocytopenic purpura

The American Journal of Medicine, 1957
A 40-year-old obese black woman has had weakness and epigastric pain for several weeks and diarrhea and vomiting for four days. She does not appear acutely ill; the physical examination is normal except for abdominal tenderness. Her hematocrit is 25 percent. The platelet count is 10,000 per cubic millimeter.
H F, RODRIGUEZ, D F, BABB, E, PEREZ SANTIAGO, J, COSTAS-DURIEUX   +3 more
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Thrombotic Thrombocytopenic Purpura

Pediatric Emergency Care, 2011
In 1924, Dr Eli Moschcowitz described a 16-year-old adolescent girl with abrupt onset of petechiae, hemolytic anemia, followed by paralysis, coma, and death. Autopsy showed widespread hyaline thrombi in the terminal arterioles and capillaries of various organs. The syndrome described by Moschowitz is now known as thrombotic thrombocytopenic purpura.
Alex, Koyfman, Elizabeth, Brém, Vincent W, Chiang   +2 more
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Thrombotic thrombocytopenic purpura

Blood Coagulation & Fibrinolysis, 1992
Thrombotic thrombocytopenic purpura is an uncommon disorder, but it continues to be of considerable interest. The disease mechanisms are unclear and the aetiology is unknown. Perhaps most enigmatic of all, the mode of action of plasma therapy, which successfully induces remission in about two-thirds of cases, is wholly inexplicable. There are currently
W G, Murphy, J C, Moore, T E, Warkentin, C P, Hayward, J G, Kelton   +4 more
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Thrombotic thrombocytopenic purpura

Disease-a-Month, 2014
Moschowitz first described thrombotic thrombocytopenic purpura (TTP) in 1925 in a 16-yearold female who presented with fever, petechiae, and a microangiopathic hemolytic anemia. Autopsy examination at the time revealed hyaline thrombi in the vascular beds of many organs. By 1947, several more cases were described and Singer suggested the term TTP.
Albara, Said, Rami Y, Haddad, Robert, Stein, Edgar V, Lerma   +3 more
openaire   +2 more sources

Thrombotic thrombocytopenic purpura

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
A 34-year old primipara was admitted to hospital with dichorionic-diamniotic twins in 26+3 weeks of gestation. In suspicion of HELLP-syndrome, caesarean section was performed at 27+4 weeks of gestation, because of platelet count was reduced to 44000/µl. A re-laparotomy had to be performed because of intra-abdominal bleedings.
Charlotte, Kaiser, Ulrich, Gembruch, Viktor, Janzen, Anne-Sybil, Gast   +3 more
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Thrombotic thrombocytopenic purpura

The American Journal of Medicine, 1952
Abstract 1.1. The clinical and pathologic observations of two cases of thrombotic thrombocytopenic purpura are presented. 2.2. This condition is characterized by the clinical triad of (1) hemolytic anemia; (2) thrombocytopenic purpura and (3) mental and neurologic abnormalities which may be bizarre or transient.
B R, GENDEL, J M, YOUNG, A P, KRAUS
openaire   +4 more sources

Thrombotic Thrombocytopenic Purpura

JAMA: The Journal of the American Medical Association, 1991
CASE PRESENTATION —Charles T. Bingham III, MD A 27-YEAR-OLD man was transferred to The Johns Hopkins Hospital for evaluation of delirium. Five days prior to admission he had presented to another hospital with hematemesis and syncope. Esophagogastroduodenoscopy revealed the presence of a 0.5-cm gastric ulcer.
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Thrombotic Thrombocytopenic Purpura

Thrombosis and Haemostasis, 1995
Recent studies indicate that CRTTP patients have excessive shear stress-induced platelet aggregation that is associated with the presence of ULvWF multimers in their plasma and increased vWF-binding to their platelets by flow cytometry. In these CRTTP patients, relapses, excessive shear-aggregation and the presence in their plasma of ULvWF forms are ...
openaire   +2 more sources